by Beth Israel Deaconess Medical Center Credit: Pixabay/CC0 Public Domain Renal cell carcinoma (RCC) is the most common form of kidney cancer. In 2018, there were an estimated 403,000 new cases of RCC and 175,000 deaths due to kidney cancer worldwide. Currently, the 5-year survival rate for patients with metastatic RCC is only about 12 percent....
by Dana-Farber Cancer Institute A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. The report in Nature Medicine suggests that if validated in larger trials and applied widely, the non-invasive...
by Deborah Wormser, UT Southwestern Medical Center A UT Southwestern researcher led a team that identified a new vulnerability in kidney tumors, the 10th most common cause of cancer death in men and women. In their investigation of the most common type of kidney cancer, called clear cell renal cell carcinoma (ccRCC), Qing Zhang, Ph.D.,...
UNIVERSITY OF EAST ANGLIA A simple urine test under development for prostate cancer detection can now use urine samples collected at home – according to new research from University of East Anglia and the Norfolk and Norwich University Hospital. Scientists pioneered the test which diagnoses aggressive prostate cancer and predicts whether patients will require treatment...
by University of California, San Francisco UCSF Benioff Children’s Hospitals have successfully treated a months-old infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer. The decision to use the drug, sorafenib, was made after pathologists identified a unique mutation in the form of...
ERA-EDTA The link between brain dysfunction and advanced kidney disease was first noted in 1930, so it is not a new finding. Experts spoke of ‘dialysis dementia’ or ‘uremic encephalopathy’. What is new, however, is the finding that mild cognitive impairment (MCI) may already be present in earlier stages of CKD, affecting approximately one in two CKD patients (prevalence varies in studies between...
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results will be presented April 2 at...
BOSTON – A combination of two drugs – one of them an immunotherapy agent – could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial. Patients who received the immunotherapy drug avelumab plus axitinib, a targeted agent,...
“You see this place on the image? That’s where your kidney was,” says VCU Massey Cancer Center medical oncologist Asit Paul, M.D., Ph.D., to 69-year-old Thomas Bland. “And the tumors we saw in your lung and other places still have not returned. I’m happy to say you’ve been disease-free for more than two-and-a-half years.” Asit...
DALLAS – Aug. 28, 2018 – In order to halt the growth of cancer cells, you have to know what feeds them. Researchers at the nationally recognized Kidney Cancer Program at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center have developed a novel approach using glucose that may open up new opportunities for therapeutic intervention. IMAGE: DR. RALPH DEBERARDINIS AND HIS LAB MANAGER, JESSICA SUDDERTH,...
