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Melatonin shown to protect kidney damage caused by obesity with diabetes
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Melatonin shown to protect kidney damage caused by obesity with diabetes

by  University of Granada Dr. Ahmad Agil. Credit: University of Granada Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (U.S.) have taken an important step in the fight against kidney damage and its progression toward kidney failure, which is closely related to diabesity (obesity with type...

Compound found in some vegetables may reduce diabetes-related kidney damage
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Compound found in some vegetables may reduce diabetes-related kidney damage

EXPERIMENTAL BIOLOGY IMAGE: A SCHEMATIC ILLUSTRATING HOW PEITC TREATMENT AFFECTED INDUCED NEPHROPATHY IN RATS BY MODULATING GLYCATIVE STRESS, OXIDATIVE STRESS AND INFLAMMATORY PATHWAYS. CREDIT: IMAGE COURTESY OF MOHAMED EL-SHERBINY, ALMAAREFA UNIVERSITY. New research conducted in rats suggests a compound that gives some cruciferous vegetables their pungent taste could help to reverse kidney problems associated with diabetes.  It...

Kidney-on-a-chip offers clues to prevent kidney damage from essential drugs
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Kidney-on-a-chip offers clues to prevent kidney damage from essential drugs

by Adrienne Williamson , Medical Xpress A human kidney spheroid with embedded oxygen sensors (orange). Credit: A. Cohen et al., Science Translational Medicine (2021) There are 1.5 million cases of drug-induced kidney toxicity each year in the U.S. Among the usual suspects are cyclosporin and cisplatin, a pair of widely used chemotherapy drugs. Because both...

COVID-19: Exercise may protect against deadly complication
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COVID-19: Exercise may protect against deadly complication

by University of Virginia A review by Zhen Yan, Ph.D., of the University of Virginia School of Medicine, showed that medical research findings “strongly support” the possibility that exercise can prevent or at least reduce the severity of ARDS, which affects between 3% and 17% of all patients with COVID-19. Based on available information, the...

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Charcoal-based drug delivery system improves efficacy of common herpes drug

by Sharon Parmet, University of Illinois at Chicago A study led by researchers from the University of Illinois at Chicago has found that combining acyclovir—a commonly prescribed topical herpes medication—with particles of activated carbon improves efficacy of the drug. This new approach allows for less frequent dosing and overall course of treatment while providing some...

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NSAID pretreatment impairs immune response in heart failure, worsens heart and kidney damage

Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. However, prolonged use raises the risk of heart and kidney failure events. A heart attack causes death of heart muscle cells by lack of oxygen, and it also significantly injures the kidneys. To understand the molecular and cellular mechanisms...

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Drinking soda after exercise could damage kidneys – patient education

Downing a cool soft drink after a hot workout can feel refreshing. However, according to the latest research, it may cause further dehydration and interfere with kidney function. A new study looks at soda’s impact on the kidneys Exercise soda A new study looks at soda’s impact on the kidneys. Caffeinated soft drinks that are...

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Study shows how lixisenatide slows or prevents damage to the kidneys in patients with type 2 diabetes and cardiovascular disease

New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) and published simultaneously in The Lancet Diabetes & Endocrinology shows how the glucose-lowering drug lixisenatide can slow or prevent damage to the kidneys in macro-albuminuric patients with type 2 diabetes mellitus (T2DM) and cardiovascular disease. The study is...

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Test for antibiotic associated kidney damage in children with cystic fibrosis identified

New research, published in Nature Scientific Reports, conducted by the University and partners highlights effective methods for identifying a common side effect in children receiving drug treatments for Cystic fibrosis. The genetic disorder, cystic fibrosis (CF) is characterized by secondary bacterial lung infections, often by a specific resistant bacteria, Pseudomonas aeruginosa. Antibiotics known as aminoglycosides have good efficacy...