by St. Jude Children’s Research Hospital This work shows for the first time that a type of immune cell called a patrolling monocyte plays a critical role in lupus-related kidney disease. Authors Vanessa Redecke, M.D., Ph.D., Hans Haecker, M.D., Ph.D., and Jeeba Kuriakose, Ph.D. Credit: St. Jude Children’s Research Hospital A study led by St. Jude Children’s Research...
Tag: <span>Kidney disease</span>
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Older adults starting dialysis die at higher rates than previously thought
Study results can help inform patient decisions, physician choice of treatment for end-stage kidney disease HARVARD MEDICAL SCHOOL Older adults with end-stage kidney disease who start dialysis–a treatment that keeps their blood free of toxins–appear to die at higher rates than previously thought, according to findings of a new study by researchers at Harvard Medical School, Brigham and Women’s Hospital, Veterans Affairs Boston Healthcare System...
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Itchy skin affects the health and quality of life of many patients with kidney disease
by American Society of Nephrology New research reveals that pruritus, or itchy skin, affects a substantial percentage of patients with chronic kidney disease(CKD). The study, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), also indicates which patients are more likely to experience pruritus, and demonstrates that pruritus may affect quality of life and sleep. In studies of patients on dialysis, pruritus is common and has...
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Research ties common heartburn medications to kidney disease and failure
Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increases the risk of chronic kidney disease by 20 percent and raises the risk of kidney failure by four times. Risks were highest...
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New kidney research sheds light on harms of certain drugs
Scientists have identified an enzyme that is a “master regulator” of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals. IMAGE: THIS IS A TRANSMISSION ELECTRON MICROSCOPIC PICTURE OF THE FILTRATION BARRIER OF THE KIDNEY- FOOT PROCESSES OF...
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Researchers discover kidney disease gene affects more populations than previously thought
Until now, studies on the APOL1 gene have primarily focused on African and African American populations THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE New York, NY (December 27, 2018) — In the largest population genomics investigation to date, a team of researchers at the Icahn School of Medicine at Mount Sinai, Stanford University, and the...
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Sugar-sweetened beverage pattern linked to higher kidney disease risk
Higher collective consumption of sweetened fruit drinks, soda, and water was associated with a higher likelihood of developing chronic kidney disease (CKD) in a community-based study of African-American adults in Mississippi. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), contribute to the growing body...
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Gene editing possible for kidney disease
For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalised treatment in the future. Experts at Newcastle University, UK, have shown in a cell model and in a mouse model that gene editing could be used for Joubert syndrome to stop...
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Researchers show that a high-protein diet does not affect kidney function
A widely held and controversial myth that high-protein diets may cause kidney damage in healthy adults has been debunked by scientists at McMaster University, who examined more than two dozen studies involving hundreds of participants. Credit: CC0 Public Domain The meta-analysis, published in the Journal of Nutrition, challenges the perceived dangers of a protein-rich diet,...
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“Atypical” virus discovered to be driver of certain kidney diseases
An international research team led by Wolfgang Weninger has discovered a previously unknown virus that acts as a “driver” for certain kidney diseases (interstitial nephropathy). This “atypical” virus, which the scientists named “MKPV” (for Mouse Kidney Parvovirus), belongs to the family of parvoviruses. The results of the study have now been published in the leading...