Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increases the risk of chronic kidney disease by 20 percent and raises the risk of kidney failure by four times. Risks were highest...
Tag: <span>Kidney disease</span>
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New kidney research sheds light on harms of certain drugs
Scientists have identified an enzyme that is a “master regulator” of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals. IMAGE: THIS IS A TRANSMISSION ELECTRON MICROSCOPIC PICTURE OF THE FILTRATION BARRIER OF THE KIDNEY- FOOT PROCESSES OF...
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Researchers discover kidney disease gene affects more populations than previously thought
Until now, studies on the APOL1 gene have primarily focused on African and African American populations THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE New York, NY (December 27, 2018) — In the largest population genomics investigation to date, a team of researchers at the Icahn School of Medicine at Mount Sinai, Stanford University, and the...
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Sugar-sweetened beverage pattern linked to higher kidney disease risk
Higher collective consumption of sweetened fruit drinks, soda, and water was associated with a higher likelihood of developing chronic kidney disease (CKD) in a community-based study of African-American adults in Mississippi. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), contribute to the growing body...
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Gene editing possible for kidney disease
For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalised treatment in the future. Experts at Newcastle University, UK, have shown in a cell model and in a mouse model that gene editing could be used for Joubert syndrome to stop...
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Researchers show that a high-protein diet does not affect kidney function
A widely held and controversial myth that high-protein diets may cause kidney damage in healthy adults has been debunked by scientists at McMaster University, who examined more than two dozen studies involving hundreds of participants. Credit: CC0 Public Domain The meta-analysis, published in the Journal of Nutrition, challenges the perceived dangers of a protein-rich diet,...
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“Atypical” virus discovered to be driver of certain kidney diseases
An international research team led by Wolfgang Weninger has discovered a previously unknown virus that acts as a “driver” for certain kidney diseases (interstitial nephropathy). This “atypical” virus, which the scientists named “MKPV” (for Mouse Kidney Parvovirus), belongs to the family of parvoviruses. The results of the study have now been published in the leading...
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Caffeine consumption may extend life expectancy for people with kidney disease
A new study in Nephrology Dialysis Transplantation indicates that consuming more caffeine may help reduce the risk of death for people with chronic kidney disease. An inverse relationship between coffee consumption and mortality has been reported in the general population. However, the association between caffeine consumption and mortality for people with chronic kidney disease remains...
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In kidney disease patients, illicit drug use linked with disease progression and death
In a study of patients with chronic kidney disease (CKD), persistent substance use—especially of hard illicit drugs—was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). CKD is common in the United States, and affected patients are at higher risk for poor...
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New compound stops progressive kidney disease in its tracks
Progressive kidney diseases, whether caused by obesity, hypertension, diabetes, or rare genetic mutations, often have the same outcome: The cells responsible for filtering the blood are destroyed. Reporting in Science, a team led by researchers from the Broad Institute of MIT and Harvard, Brigham and Women’s Hospital, and Harvard Medical School describes a new approach to...