Tag: <span>Kidney disease</span>

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A new drug target for kidney disease
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A new drug target for kidney disease

by Kyoto University A new study led by ASHBi Professor Motoko Yanagita finds the suppression of two molecules, CD153 and CD30, expressed on immune cells mitigates the progression of kidney disease. Credit: Kyoto University Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective...

Kidney disease is a problem for cerebral palsy patients. Why are doctors missing it?
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Kidney disease is a problem for cerebral palsy patients. Why are doctors missing it?

by Noah Fromson,  University of Michigan Credit: CC0 Public Domain Cerebral palsy and kidney disease can be deeply intertwined. In childhood, the effects of the neurodevelopmental condition—like decreased physical activity and urologic dysfunction—are risk factors for kidney disease. The adverse relationship continues through adulthood as those with cerebral palsy often have high blood pressure, another risk for developing kidney problems. What’s more, a recent Michigan...

Study shows effectiveness of low-cost medicine in treating high blood pressure in people with advanced kidney disease
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Study shows effectiveness of low-cost medicine in treating high blood pressure in people with advanced kidney disease

by  Indiana University School of Medicine Rajiv Agarwal, MD, professor of medicine at Indiana University School of Medicine. Credit: IU School of Medicine An all Indiana University School of Medicine team of researchers led by, Rajiv Agarwal, MD, professor of medicine and staff physician at the Roudebush VA, and including Arjun Sinha, MD, associate professor of clinical medicine...

Increased temperatures contributed to more than 200,000 cases of kidney disease in 15 years in Brazil alone, world’s largest study finds
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Increased temperatures contributed to more than 200,000 cases of kidney disease in 15 years in Brazil alone, world’s largest study finds

MONASH UNIVERSITY IMAGE: PROFESSOR YUMING GUO CREDIT: MONASH UNIVERSITY Today the world’s largest study of the impact of temperature changes and kidney disease reveals that 7.4 percent of all hospitalizations for renal disease can be attributed to an increase in temperature. In Brazil – where the study was focused – this equated to more than...

Are Too Many Older Adults Told They Have Kidney Disease?
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Are Too Many Older Adults Told They Have Kidney Disease?

By Jane E. Brody If the public has learned anything about medicine during the Covid-19 pandemic, it is that science is constantly evolving. New findings can change how experts define a given illness, as well as how they diagnose, prevent and treat it. Such is the case, a new study suggests, with chronic kidney disease. A...

The ‘PodoSighter’ uses AI to identify a key indicator of early kidney disease
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The ‘PodoSighter’ uses AI to identify a key indicator of early kidney disease

by Ellen Goldbaum, University at Buffalo UB researchers have leveraged the power of digital pathology and computational modeling to develop a new approach to detecting and quantifying podocytes, shown above, a specialized type of cell in the kidney that undergoes damaging changes during early stage kidney disease. Credit: NIH, National Institute of Diabetes and Digestive...

Study: Genetic kidney disorder reversible in preclinical models
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Study: Genetic kidney disorder reversible in preclinical models

by Jane E. Dee,  Yale University Fig. 1: Reactivation of Pkd2 reverses cyst formation. Credit: DOI: 10.1038/s41588-021-00946-4 Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation and fibrosis, or scarring. The disease...

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Skipping simple urine test leaves high-risk groups with untreated kidney disease

Despite their higher risk of chronic kidney disease, people with hypertension or diabetes usually are not given a simple test for protein in the urine to screen for this potentially deadly disorder, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health. The researchers analyzed data on nearly four million...

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Weight fluctuations may predict poor outcomes in adults with kidney disease

AMERICAN SOCIETY OF NEPHROLOGY In individuals with kidney disease, those with high body mass index variability faced higher risks of needing kidney replacement therapy, experiencing a heart attack, experiencing a stroke, and dying prematurely. Washington, DC (August 12, 2021) — A recent study has linked weight fluctuations—or body mass index variability—to higher risks of cardiovascular-related problems...