by Australian National University Graphical abstract. Credit: DOI: 10.1016/j.xcrm.2021.100469 For the first time researchers have identified a gene which shows the kidney has its own way of resisting damage. The finding has major implications—especially for Indigenous people with kidney diseases such as Tiwi Islanders. The study, published in Cell Reports Medicine, sequenced the genome of patients with autoimmune...
by Kyoto University A new study led by ASHBi Professor Motoko Yanagita finds the suppression of two molecules, CD153 and CD30, expressed on immune cells mitigates the progression of kidney disease. Credit: Kyoto University Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective...
by Noah Fromson, University of Michigan Credit: CC0 Public Domain Cerebral palsy and kidney disease can be deeply intertwined. In childhood, the effects of the neurodevelopmental condition—like decreased physical activity and urologic dysfunction—are risk factors for kidney disease. The adverse relationship continues through adulthood as those with cerebral palsy often have high blood pressure, another risk for developing kidney problems. What’s more, a recent Michigan...
by Indiana University School of Medicine Rajiv Agarwal, MD, professor of medicine at Indiana University School of Medicine. Credit: IU School of Medicine An all Indiana University School of Medicine team of researchers led by, Rajiv Agarwal, MD, professor of medicine and staff physician at the Roudebush VA, and including Arjun Sinha, MD, associate professor of clinical medicine...
MONASH UNIVERSITY IMAGE: PROFESSOR YUMING GUO CREDIT: MONASH UNIVERSITY Today the world’s largest study of the impact of temperature changes and kidney disease reveals that 7.4 percent of all hospitalizations for renal disease can be attributed to an increase in temperature. In Brazil – where the study was focused – this equated to more than...
By Jane E. Brody If the public has learned anything about medicine during the Covid-19 pandemic, it is that science is constantly evolving. New findings can change how experts define a given illness, as well as how they diagnose, prevent and treat it. Such is the case, a new study suggests, with chronic kidney disease. A...
by Ellen Goldbaum, University at Buffalo UB researchers have leveraged the power of digital pathology and computational modeling to develop a new approach to detecting and quantifying podocytes, shown above, a specialized type of cell in the kidney that undergoes damaging changes during early stage kidney disease. Credit: NIH, National Institute of Diabetes and Digestive...
by Jane E. Dee, Yale University Fig. 1: Reactivation of Pkd2 reverses cyst formation. Credit: DOI: 10.1038/s41588-021-00946-4 Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation and fibrosis, or scarring. The disease...
COVID-19 long-haulers, even those with mild infections of the virus, experience significant decline in kidney function, according to a deep dive into federal health data. The findings add to concerns that many people who have had COVID-19 go on to suffer a range of adverse conditions months after their initial infections. The data show that...
Despite their higher risk of chronic kidney disease, people with hypertension or diabetes usually are not given a simple test for protein in the urine to screen for this potentially deadly disorder, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health. The researchers analyzed data on nearly four million...
