New data show advantage of add-on therapy with belimumab in lupus nephritis Systemic lupus erythematosus (SLE) is a chronic, inflammatory, autoimmune disease, in which damage is caused to multiple organs and tissues by the formation and deposition of immune complexes (antigen-antibody complexes). The kidneys are also affected in about half of the patients when immune...
Tag: <span>kidney</span>
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Sugary soda consumption linked to reduced kidney blood flow
by American Physiological Society Regular consumption of sugary soda sweetened with high-fructose corn syrup (HFCS) reduces kidney blood flow, which could be linked to a greater risk of developing chronic kidney disease (CKD), according to a recently published paper in the American Journal of Physiology-Renal Physiology. The study, chosen as an APSselect article for May,...
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Innovative approach offers option for treating upper tract urothelial cancer
Treatment of low-grade upper tract urothelial cancer usually involves radical surgery to remove the kidney and ureter, highlighting the need for improved treatments. An international team led by researchers at Baylor College of Medicine reports in the journal The Lancet Oncology that an innovative form of local chemotherapy using a mitomycin-containing reverse thermal gel offers...
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Drug shows promise in reversing kidney damage caused by lupus
by Yale University A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine. “Kidney damage affects about half of the patients with lupus, sometimes leading to renal failure with a...
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Sweet nanoparticles trick kidney
UNIVERSITY OF FREIBURG In the past decade nanomedicine has contributed to better detection and treatment of cancer. Nanoparticles are several 100 times smaller than the smallest grain of sand and can therefore easily travel in the blood stream to reach the tumor. However, they are still too big to be removed by the kidneys. Since...
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Kidney stem cells can be isolated from urine
Publication in Scientific Reports HEINRICH-HEINE UNIVERSITY DUESSELDORF Researchers from the Institute for Stem Cell Research and Regenerative Medicine (ISRM) at the medical faculty of Heinrich Heine University-Duesseldorf under the directorship of Prof. Dr. James Adjaye have developed a protocol for the reproducible isolation and characterization of kidney stem cells, urine derived renal progenitor cells (UdRPCs)...
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Study reveals ‘identical’ survival for kidney dialysis patients using different treatments
Research carried out at University of Limerick has shown that life expectancy outcomes for two of the most common forms of kidney dialysis treatment are “virtually identical”. In the largest study of its kind, researchers from the Graduate Entry Medical School (GEMS) at UL compared the survival of patients with kidney failure that were treated...
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Parkinson’s Disease and Your Bladder
Anne Pelletier-Cameron, M.D., often jokes to her patients that she’s a female plumber of the lower urinary tract. On a more professional note, however, she’s a urologist in the Michigan Medicine Department of Urology. In this role, Pelletier-Cameron treats patients with a variety of lower urinary tract symptoms. Some of her patients have been diagnosed...
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Implantable artificial kidney achieves preclinical milestone
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference in Washington, DC. The team will report that UC...
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Acute kidney injury often seen with checkpoint inhibitor use
Harish Seethapathy, M.B.B.S., from Massachusetts General Hospital in Boston, and colleagues examined the frequency, severity, etiology, and predictors of AKI among patients receiving checkpoint inhibitor therapy from May 2011 to December 2016. Data were included for 1,016 patients (average age, 63 years). The researchers found that overall, 17 percent of patients receiving checkpoint inhibitor therapy...