Pegilodecakin with pembrolizumab and nivolumab shown to be safe in Phase 1B study UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER HOUSTON — Pegilodecakin, a first-in-class drug currently in clinical trials, has shown positive safety results and may offer a potential new treatment avenue for patients with non-small cell lung cancer (NSCLC) and kidney cancer....
Tag: <span>kidney</span>
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Human kidney map charts our growing immune defense
New cell atlas reveals immune cells present in zones of human kidney WELLCOME TRUST SANGER INSTITUTE The first cell atlas of the human kidney’s immune system has been created after scientists mapped nearly 70,000 individual kidney cells from early life and adults. Researchers at the Wellcome Sanger Institute, University of Cambridge, Newcastle University and their...
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Treatment doctor tested on himself can put others into remission
by Perelman School of Medicine at the University of Pennsylvania Five years ago, David C. Fajgenbaum, MD, MBA, MSc, both a Penn Medicine researcher and patient, tried an experimental treatment on himself based on his laboratory research findings in the hopes of saving his own life. He has been in remission ever since. Now his...
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Through the kidneys to the exit
Scientists from NUST MISIS learn how to safely excrete nanomedicine NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY MISIS Scientists at the National University of Science and Technology “MISIS” (NUST MISIS) have identified a new mechanism for removing magnetic nanoparticles through the kidneys, which will help to create more effective and safe drugs. The results of the...
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What causes pain in the right upper quadrant of the ribs?
By Beth Sissons Reviewed by Saurabh (Seth) Sethi, MD MPH Healthcare professionals consider the abdomen to have four sections, which they call quadrants. This classification helps them better identify symptoms. The right upper quadrant (RUQ) includes the pancreas, right kidney, gallbladder, liver, and intestines. Pain under the ribs in this area can indicate a health problem affecting one of these organs or the surrounding tissues....
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Atrasentan tied to lower risk for kidney events in T2DM with CKD
(HealthDay)—Atrasentan is associated with a reduced risk for renal events in patients with type 2 diabetes and chronic kidney disease, according to a study published online April 14 in The Lancet to coincide with the International Society of Nephrology World Congress of Nephrology, held from April 12 to 15 in Melbourne, Australia. Hiddo J.L. Heerspink, Ph.D., from the University of Groningen in the Netherlands,...
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Kidneys and blood pressure connection
Posted by Kathleen Hoffman on Mar 31, 2019 in Blog It doesn’t seem possible that high blood pressure numbers can damage kidneys. But the way kidneys work can give you an understanding of the reason. Below is an infographic explaining the important filtration parts of the kidneys–nephrons. In the kidneys, the delicate structures called nephrons are filtering wonders. The blood moves into...
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Biotech’s brash entrepreneur finally finds drug-development success with overactive bladders
By ADAM FEUERSTEIN @adamfeuerstein MARCH 19, 2019 Vivek Ramaswamy, the hedge fund manager turned biotech entrepreneur, has raised billions of dollars to create a constellation of “Vant” companies that license and develop drugs from other firms. Five years and one spectacular Alzheimer’s drug blowup later, Ramaswamy finally notched a late-stage clinical trial win. It comes courtesy of Urovant, the urology-focused spinout from his Roivant...
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Antibodies to a Retina Protein to Be Used as a Kidney Cancer Marker
Sechenov University together with their German colleagues suggest a new highly sensitive, quick, and pain-free method for diagnosing kidney cancer. This method is based on measuring of the immune response to arrestin-1, a retina protein that is synthesized in the cancerous cells of kidneys. Tumors can be benign or malignant. The first ones are not extremely dangerous but they can...
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Sugar-sweetened beverage pattern linked to higher kidney disease risk
Higher collective consumption of sweetened fruit drinks, soda, and water was associated with a higher likelihood of developing chronic kidney disease (CKD) in a community-based study of African-American adults in Mississippi. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), contribute to the growing body...