About 40 million people who will need insulin to manage their type 2 diabetes in 12 years’ time will not get it unless access to the drug is significantly improved, according to new research. Diagnoses of type 2 diabetes are soaring worldwide, linked to the obesity epidemic. Not all of those diagnosed will need insulin,...
Tag: <span>kidney</span>
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Stage four sarcomatoid kidney cancer patient first to show complete response to immunotherapy
“You see this place on the image? That’s where your kidney was,” says VCU Massey Cancer Center medical oncologist Asit Paul, M.D., Ph.D., to 69-year-old Thomas Bland. “And the tumors we saw in your lung and other places still have not returned. I’m happy to say you’ve been disease-free for more than two-and-a-half years.” Asit...
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Genetic variants reveal new targets for chronic kidney disease treatment
The kidney does more than double or even triple duty compared to other organs—it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones. Given this complexity, when things go wrong, havoc can ensue, causing a suite of symptoms called chronic kidney disease (CKD), which includes toxin accumulation, fatigue, and high blood...
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This tiny particle might change millions of lives
Nanoparticle targets kidney disease for drug delivery UNIVERSITY OF SOUTHERN CALIFORNIA Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That’s what it’s like to sneak a targeted drug into a kidney and keep it from...
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‘Artificial’ kidney that could mean thousands won’t need dialysis or a transplant
Implant that mimics functions of the human kidney could begin trials this year It could be a life-saving option for patients with chronic kidney disease If successful it would save patients from dialysis or needing a transplant A coffee cup-sized implant that mimics the functions of the human kidney could be a life-saving option for patients...
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Mitochondrial dysfunction contributes to kidney disease
Scientists found a previously unknown link between mitochondria and kidney disease, identifying a receptor that causes kidney dysfunction when suppressed, according to a study published in Proceedings of the National Academy of Sciences. The receptor—estrogen-related receptor gamma (ERRγ)—regulates mitochondrial metabolism, and was also found in unusually low levels in patients with chronic kidney disease, pointing to its...