by Kerstin Wild, Leibniz Institute for Immunotherapy Wound healing and target killing are both effector mechanisms of CD8 T cells. (A) Combined proliferation and killing assay in the presence of influenza-specific CD8 T cells and varying amounts of pulsed peptides on MRC-5 and HaCaT cells seeded in a 30:70 ratio. Left, representative image with labels...
By Michael Irving July 24, 2023 In patients that successfully beat cancer, scientists have discovered new “superior” T cells that can attack multiple cancer targets Depositphotos Scientists have discovered a previously unknown type of immune cell that develops in people who successfully fight off cancer. Unlike other killer T cells, these home in on multiple...
by Claudia Ehrlich, Universität des Saarlandes Dr. Annette Lis (R) and Dorina Zöphel (L) of Saarland University are studying how the activity of killer cells changes as the cells age. Credit: Oliver Dietze The human immune system is a thing of wonder. Up until now it had been widely assumed that the ability of killer...
by University of Geneva Killer-T cells (green) attack lymphatic vessels (red) in tumours and induce their death (cell death marker in white). Credit: UNIGE – Robert Pick / Stéphanie Hugues To grow, tumors rely on a specific structure, the tumor stroma. This includes blood vessels, which provide the nutrients necessary for the multiplication of diseased...
BY MITCH LESLIE 8 MAR 2022 10:00 AM A newly identified class of the human immune system’s T cells may kill other T cells, helping wind down attacks on infections and suppressing autoimmune conditions. DAVID SCHARF/SCIENCE SOURCE The price for a vigilant immune system that can pounce on tumor cells or pathogens is occasional friendly...
by Salk Institute Credit: CC0 Public Domain In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized “killer” T cells. Salk researchers led by Professor Susan Kaech have found that the environment inside tumors (the tumor microenvironment) contains an abundance of oxidized fat molecules, which, when ingested by the...
Heidi Ledford A T cell targeting coronavirus particles (illustration).Credit: Juan Gaertner/SPL Concerns about coronavirus variants that might be partially resistant to antibody defences have spurred renewed interest in other immune responses that protect against viruses. In particular, scientists are hopeful that T cells — a group of immune cells that can target and destroy virus-infected...
UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research. The study, conducted in mice and published in...
