Health & Wellbeing By Paul McClureJuly 28, 2024 Trials of an off-the-shelf stem cell therapy for osteoarthritis significantly improved pain and functionDepositphotos A single injection of a new, off-the-shelf stem cell therapy for knee osteoarthritis significantly improved pain and function for up to 12 months in 75% of participants involved in a clinical trial. The...
by Wiley Credit: CC0 Public DomainCell therapy represents a potential regenerative treatment for osteoarthritis. A recent analysis of all relevant published studies indicates that stem cell transplantation from different sources is effective for treating knee osteoarthritis, the most prevalent chronic joint disease. The review and meta-analysis, which is published in the Journal of Orthopaedic Research,...
by Wiley Credit: CC0 Public Domain In a study published in Arthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defects of knee osteoarthritis and a lower likelihood that such defects would progress, or get worse. Researchers examined radiographic analyses of knees at baseline and at 4...
by Wiley Credit: CC0 Public Domain In a study published in Arthritis & Rheumatology that included individuals aged 50 years and older who had knee osteoarthritis, those who walking for exercise were less likely to develop frequent knee pain. The study, which included 1,212 participants, also found preliminary evidence that walking for exercise might modify some of...
by Northwestern University Credit: CC0 Public Domain Dr. Prakash Jayabalan has long pondered why more non-operative treatment options aren’t available to patients with knee osteoarthritis (OA), particularly because it is the most common cause of disability in the U.S. “Doctors perform approximately 1 million surgical knee replacements each year,” he said. “Of course, a proportion...
by Gillian Rutherford, University of Alberta Credit: Pixabay/CC0 Public Domain Female astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be developed for knee osteoarthritis in women here on Earth—based on newly published research on the sex differences in knee meniscus tissue. Knee osteoarthritis is more common in females than...
by Jennifer Stranges, St. Michael’s Hospital Treatment effect on osteoarthritis pain and dropouts due to adverse events compared with oral placebo, ordered according to treatment effect size on osteoarthritis pain. Blue: oral non-steroidal anti-inflammatory drugs; green: topical non-steroidal anti-inflammatory drugs; orange: opioids. Area between dashed lines shows treatment effect estimates below the minimum clinically important difference....
WILEY Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Professionals, estimates that 858,000 Americans use opioids such as tramadol and oxycodone for...
Knee osteoarthritis is a condition when the natural cushioning between knee joints (cartilage) wears away. Although it is commonly known as wear-and-tear arthritis, young people can get it too and it may even be hereditary. Knee osteoarthritis causes pain, which is usually addressed with paracetamol and nonsteroidal anti-inflammatory drugs. Now scientists from the University of...
by Alison Ramsay, University of Aberdeen A study by scientists has discovered that therapeutic exercise does not harm articular cartilage of the knee in people with osteoarthritis, a leading cause of disability worldwide associated with pain, impaired mobility and quality of life. It may, in fact, benefit articular cartilage. Despite physical exercise (including therapeutic exercise) being one of the three key osteoarthritis treatment...
