UNIVERSITY OF EASTERN FINLAND The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a new study led by the University of Eastern Finland. Different mutations in the same amino acid of the KRAS protein have so varied effects on protein function that they may require...
Tag: <span>KRAS mutant cancer</span>
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Researchers develop new strategy to target KRAS mutant cancer
Although KRAS is one of the major oncogenes associated with aggressive cancers, drugs designed to block KRAS function have not been able to halt cancer progression in a clinical setting. Until now, KRAS has remained infamously “undruggable.” In a new study, published this month in Cancer Discovery, University of California San Diego School of Medicine researchers...