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Researchers determine first crystal structure of LAG3 protein; findings could yield better cancer therapy approaches
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Researchers determine first crystal structure of LAG3 protein; findings could yield better cancer therapy approaches

by H. Lee Moffitt Cancer Center & Research Institute LAG3 Crystal Structure. Credit: Moffitt Cancer Center Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors target the proteins PD-1 and CTLA-4 and...