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For large bone injuries, it’s Sonic hedgehog to the rescue
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For large bone injuries, it’s Sonic hedgehog to the rescue

by Keck School of Medicine of USC AMer surgical rib resec/on (top), a car/lage and bone bridge form (second from top) and then resolve (third from top) and remodel to regenerate the missing /ssue in the gap (boQom). Blue shows car/lage matrix; red shows mineralized matrix. Credit: Stephanie Kuwahara and Max Serowoky/ Mariani Lab A...