by University of Helsinki Fig. 1: Generating proliferative induced hepatocytes using defined transcription factors and oncogenic drivers. A Schematic outline of the cell transformation assay for making lineage-specific cancer by lentiviral expression of three lineage-specific TFs to convert HFs to induced hepatocytes (iHep) and defined oncogenic drivers to transform iHeps to proliferating and tumorigenic cells. B...
Tag: <span>Liver cancer cells</span>
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Liver cancer cells manipulate stromal cells involved in fibrosis to promote tumor growth
OSAKA UNIVERSITY IMAGE: THE INTERACTION BETWEEN TUMOR CELLS AND STELLATE CELLS IN TUMOR MICROENVIRONMENT v CREDIT: OSAKA UNIVERSITY Osaka, Japan – Hepatocellular carcinoma (HCC), frequently seen in patients with liver cirrhosis caused by alcohol abuse or chronic viral hepatitis, is the most common form of liver cancer worldwide. As such, it is the third-most common cause of...