Research from the University of Pittsburgh School of Medicine in animal models and patient tissues has identified a new molecular pathway in the liver that suggests a commonly used anti-rejection medication could be repurposed to treat certain liver cancers. Mouse liver tissues showing cells surrounding the central vein with active mTOR (red) and glutamine synthetase...
Tag: <span>liver cancers</span>
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New drug seeks receptors in sarcoma cells, attacks tumors in animal trials
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. Image: The new drug candidate, shown in green, fits precisely into the active site within the target protein, retonoid X receptor. Credit: Dipanjan Pan, University...