by Krista Conger, Stanford University Medical Center A study led by researchers at Stanford Medicine questions the long-held belief that adult liver cells rarely divide. Credit: Marko Aliaksandr/Shutterstock.com Intermittent fasting—abstaining from eating for lengthy periods of time—spurs liver cells in laboratory mice to divide rapidly, according to a study led by researchers at Stanford Medicine. The finding challenges the long-standing...
by University of Basel One of the main causes of liver cancer is excessive alcohol consumption. Credit: Biozentrum, University of Basel The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol...
by Anne Rommel, Leibniz-Institut für Arbeitsforschung an der TU Dortmund Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.01.020 Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile acids is unclear. The Leibniz Research Center...
by Mônica Tarantino, FAPESP Research reveals the mechanisms whereby methionine-deficient and methionine-supplemented diets can alter gene expression and damage liver cells. Credit: DBCLS and Ben Mills/Wikimedia Commons Having shown that diet can influence gene expression, science is starting to find out more about how this happens. According to an article recently published in Food and Chemical Toxicology, a...
by Wellcome Trust Sanger Institute Credit: CC0 Public Domain For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease. These mutations are specific to liver disease that is associated with obesity, type 2 diabetes, and chronic alcohol consumption. The study, from the Wellcome...
A research group led by Daniel Aili, associate professor at LiU, has developed a bioink to print tissue-mimicking material in 3D printers. The scientists have developed a method and a material that allow cells to survive and thrive. “Bioprinting is a new and exciting technology to manufacture three-dimensional tissue-mimicking cell cultures. It has been a...
by eLife Electron micrographs of hepatitis C virus purified from cell culture. Scale bar is 50 nanometers. Credit: Center for the Study of Hepatitis C, The Rockefeller University. By discovering a trick the hepatitis C virus uses to evade the immune system, scientists have identified a new antiviral defense system that could be used to...
by Perelman School of Medicine at the University of Pennsylvania “Senotherapy,” a treatment that uses small molecule drugs to target “senescent” cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and...
While poor nutrition and lack of exercise contribute to obesity, exposure to these compounds could trigger lifelong susceptibility to weight gain, Baylor University researcher says Chemical compounds found in many consumer products could be major contributors to the onset of lipid-related diseases, such as obesity, in humans, according to a Baylor University study. Until recently,...
Scientists discover previously unknown subtypes of liver cells in health and disease MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells. In addition to its role in human metabolism,...
