Content by Owlstone Medical LtdReviewed by Louis Castel The gut-liver axis is the term used to describe the two-way relationship between the gut microbiome and the liver. This relationship stems from the integration of signals produced by various factors such as diet, genetics, and the environment. The liver and the gastrointestinal tract are connected by...
FDA approves Madrigal’s NASH drug, marking the first-ever treatment for the liver diseaseNicole DeFeudisEditorMadrigal Pharmaceuticals’ NASH drug won an accelerated approval on Thursday, becoming the first treatment for a liver disease that for years has vexed scientists and investors. The medication, resmetirom, was approved under the brand name Rezdiffra for patients with stage 2 and...
ByEthan SullivaA recent study suggests an intriguing connection between dementia and liver disease. The research implies that some cases of dementia may be linked to liver health, suggesting that this connection could be treatable and potentially reversible. This new understanding could be a game-changer in the management and treatment of dementia cases linked to liver...
by Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public DomainInvestigators from the Smidt Heart Institute at Cedars-Sinai and colleagues found that women with fatty liver disease related to alcohol consumption have almost twice the risk of dying within a certain time period than men with the same condition. The findings, published in the Journal of Hepatology, highlight the...
by Higher Education Press The proposed model of hepatic TRPC3-regulated ALD. Credit: Qinchao Ding, Rui Guo, Liuyi Hao, Qing Song, Ai Fu, Shanglei Lai, Tiantian Xu, Hui Zhuge, Kaixin Chang, Yanli Chen, Haibin Wei, Daxi Ren, Zhaoli Sun, Zhenyuan Song, Xiaobing Dou, Songtao LiExcessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which...
Chinese Academy of SciencesIn the editorial published on 4 September 2023, in the “gut-liver axis” special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota...
by Boston Medical Center Graphical Abstract. Credit: Cell Stem Cell (2023). DOI: 10.1017/j.stem.2023.10.008 Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire...
by University of Montreal Credit: Pixabay/CC0 Public DomainCanadian scientists have found a new link between two major metabolic diseases: diabetes and steatotic liver disease, commonly known as fatty liver disease. Published in Diabetes, research into the two diseases by Université de Montréal medical professor Jennifer Estall and her team at the Montreal Clinical Research Institute (IRCM)...
Megan Brooks Drinking sugar-laden beverages on a regular basis may increase the risk for liver cancer and death from chronic liver disease, new research suggests. The observational analyses revealed that postmenopausal women who consumed at least one sugar-sweetened beverage daily had an 85% higher risk of developing liver cancer and a 68% higher risk of dying from...
by University of California – San Diego Credit: Pixabay/CC0 Public Domain Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with non-alcoholic steatohepatitis (NASH)-related fibrosis. The results, published in the June 24, 2023, online edition of The New England Journal of Medicine, found...
