by First Hospital of Jilin University ACLF, acute-on-chronic liver failure; APASL, Asian-Pacific Association for the Study of the Liver; INR, international normalized ratio; MELD, model for end-stage liver disease; TBiL, total bilirubin; WBC, white blood cell count. Credit: Xia Yu, Ruoqi Zhou, Wenting Tan, et al. Researchers have unveiled an advancement in liver failure care:...
Tag: <span>Liver Failure</span>
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Metabolic dysregulation and metabolite imbalances in acute-on-chronic liver failure: Impact on immune status
Peer-Reviewed Publication Xia & He Publishing Inc. image: Major changes in energy metabolism levels in ACLF (acute-on-chronic liver failure) include: (1) High levels of inflammation activate the body’s neurohumoral response axis, regulating the catabolic metabolism of peripheral organ systems (such as the liver, muscle, and adipose tissue) to provide sufficient energy for immune cells; (2)...
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One step closer to reversing liver failure: Study shows how liver is triggered to regrow when damaged
by Peter MacCallum Cancer Centre Credit: Developmental Cell (2024). DOI: 10.1016/j.devcel.2024.01.024Researchers at Peter Mac have made a key discovery in liver regeneration that may have important implications for liver cancer. Joint research by Associate Professor Andrew Cox and Professor Mark Dawson, published Feb. 15 in Developmental Cell, has identified how the liver is triggered to regrow...
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A first-ever experiment shows how pigs might one day help people who have liver failure
by The Associated Press Credit: Pixabay/CC0 Public DomainSurgeons externally attached a pig liver to a brain-dead human body and watched it successfully filter blood, a step toward eventually trying the technique in patients with liver failure. The University of Pennsylvania announced the novel experiment Thursday, a different spin on animal-to-human organ transplants. In this case,...
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Latin Americans with greater Native American ancestry may be more susceptible to liver failure
by University College London EF CLIF infographic showing results of the ACLARA study in Latin America. Credit: EF CLIF Differences in the percentage of Native American ancestry in Latin American people are linked with the chances of them developing severe liver failure and associated high risk of short-term mortality, a study co-authored by UCL has found....
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Phage therapy shows promise for treating alcoholic liver disease
KING’S COLLEGE LONDON A team of researchers including those from King’s College London and the University of California San Diego School of Medicine, have for the first time successfully applied bacteriophage (phage) therapy in mice to alcohol-related liver disease. Phages are viruses that specifically destroy bacteria. In a paper published today in Nature, the team...
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Study shows artificial intelligence can detect language problems tied to liver failure
Technology that lets humans communicate with machines adapts well to role as medical detective JOHNS HOPKINS MEDICINE Natural language processing, the technology that lets computers read, decipher, understand and make sense of human language, is the driving force behind internet search engines, email filters, digital assistants such as Amazon’s Alexa and Apple’s Siri, and language-to-language...
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Fad diets could contribute to liver disease known as a ‘silent killer’
Posted Today If you’re looking to shed a few pounds, you might be tempted to try out popular new approaches like the keto diet or fasting. But you might be unwittingly worsening a problem you don’t even know you have: a fatty liver. Doctors are worried about an increasingly common condition called nonalcoholic fatty liver...
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Non-exercisers more likely to have fatty liver disease
Reviewed by James Ives, M.Psych. (Editor) “Training with high enough intensity to improve fitness can be important both for preventing and treating fatty liver disease,” says Ilaria Croci, a postdoctoral fellow in Norwegian University of Science and Technology (NTNU)’s Cardiac Exercise Research Group and at the University of Queensland in Australia. Little known, but common You may not have heard...
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Intelligent testing could save lives by defusing ticking time bomb of liver disease
by Dominic Glasgow, University of Dundee A new way of detecting liver disease decades before it can become fatal has been developed by a team of scientists at the University of Dundee and NHS Tayside. It comes as clinicians warn of a “ticking time bomb” of alcohol-related and obesity-related liver diseases. Liver disease, which is notoriously asymptomatic, has become...
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