by The Endocrine Society Credit: Pixabay/CC0 Public Domain Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. “Two risk factors for NAFLD, obesity and diabetes,...
Tag: <span>Liver</span>
Your liver is just under three years old
by Dresden University of Technology Human liver is composed of cells with different amounts of DNA. Most of the cells have just two copies of DNA, as the cell indicated with a white arrow. Some cells accumulate more sets of DNA, like the ones indicated with yellow arrows. Those various types of cells renew differently....
How too much drinking harms the liver
As Americans stepped up their drinking during the COVID-19 pandemic, liver disease and transplants surged. Between March 2020 and January 2021, the number of U.S. patients with alcohol-associated liver disease who received a new liver or were wait-listed for a transplant was 50% higher than pre-pandemic projections, researchers say. Alcohol-associated liver disease is now the leading reason for liver...
Globins – on the hunt to protect your liver
OSAKA CITY UNIVERSITY IMAGE: MB, NGB, AND CYGB, BUT NOT HB, WERE ENDOCYTOSED INTO THE HSCS VIA ENDOCYTOSIS PATHWAY, SCAVENGED INTRACELLULAR ROS, AND SUPPRESSED COL1A1 PROMOTER ACTIVITY, RESULTING IN HSC DEACTIVATION AND INHIBITION OF COLLAGEN PRODUCTION IN VITRO AND IN VIVO. GLOBIN THERAPY COULD BE UTILIZED AS ANTI-FIBROTIC THERAPY IN HUMAN LIVER CIRRHOSIS. CREDIT: OSAKA...
A novel malaria vaccine vector – target to the liver
KANAZAWA UNIVERSITY IMAGE: THE IVIS IMAGING RESULTS FOR THE LIVERS COLLECTED FROM MICE ON DAY 8 OR DAY 224 POST-ADMINISTRATION OF AAV-LUC SHOWED THAT SYSTEMIC ADMINISTRATION OF AAV8 INDUCED ~24–43 TIMES BETTER LIVER LUCIFERASE ENZYME ACTIVITY WHEN COMPARED WITH I.M. ADMINISTRATION. CREDIT: KANAZAWA UNIVERSITY Kanazawa, Japan – Malaria remains a deadly disease that affects people...
Which medications are most toxic to the liver?
WILEY A new study published in the British Journal of Clinical Pharmacology ¬provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced liver injury (DILI), for an incidence of 0.32%. Anti-infective agents, cancer medications, and nonsteroidal...
Ultrasound pulses focused at liver help treat obesity in mouse models
By Michael Irving March 03, 2021 Tomas Huerta (left) and Sangeeta Chavan (right), researchers on the new study Feinstein Institutes for Medical Research Obesity is one of the most pressing health problems in the world today, but a new study suggests a potential non-invasive treatment. In tests in mice, researchers found that directing ultrasound pulses to the...
Study explains why patients with cancer spread to the liver have worse outcomes
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN IMAGE: WEIPING ZOU, M.D., PH.D. CREDIT: UNIVERSITY OF MICHIGAN ROGEL CANCER CENTER ANN ARBOR, Michigan — Michael Green, M.D., Ph.D., noticed that when his patients had cancer that spread to the liver, they fared poorly – more so than when cancer spread to other parts of the body. Not...
World-first study on blood hormone could reduce cardiovascular deaths
by Kim Thomas, University of Otago A simple blood test could identify seemingly-healthy people with a high hidden risk of heart disease thanks to a world-first discovery by University of Otago, Christchurch researchers. Researchers from the University’s Christchurch Heart Institute studied the blood samples and cardiology scans of 665 healthy young and middle-aged people with...
How protein protects against fatty liver
DEUTSCHES ZENTRUM FUER DIABETESFORSCHUNG DZD MICROSCOPIC IMAGES OF LIVER BIOPSIES OF THREE INDIVIDUALS WITH DIFFERENT DEGREES OF LIVER FAT ACCUMULATION view more CREDIT: DIFE Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences. A high-protein, calorie-reduced diet can cause the harmful liver fat to melt away...