Tinker Ready July 24, 2023 Editor’s note: Find the latest long COVID news and guidance in Medscape’s Long COVID Resource Center. Doctors who treat patients with long COVID, hampered by a lack of federally approved treatments, are turning to off-label use of drugs designed for addiction, diabetes, and other conditions. Those with long COVID for years now are engaging in...
Tag: <span>Long Covid</span>
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Investigating the role of T-cell immunity in long COVID
By Susha Cheriyedath, M.Sc. Jul 13 2023 Reviewed by Benedette Cuffari, M.Sc. A recent study published in Scientific Reports investigates the persistence of symptoms and the immune response in patients recovering from the coronavirus disease 2019 (COVID-19). Study: Cellular immunity reflects the persistent symptoms among COVID-19-recovered patients in Japan. Image Credit: Kateryna Kon / Shutterstock.com Background Infection with the...
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Majority of Patients With Long COVID Meet Criteria for POTS
Jul 5, 2023 John Parkinson A small study explored the connection between Postural Orthostatic Tachycardia Syndrome (POTS) and the COVID-19 condition. A new study found that (79%) of those with Post-acute sequelae of Covid-19 (PASC) or Long COVID met the internationally established criteria for POTS. The study was published in The American Journal of Medicine. “Overall,...
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Long COVID ‘Brain Fog’ Confounds Doctors, but New Research Offers Hope
Sara Novak July 03, 2023 Kate Whitley was petrified of COVID-19 from the beginning of the pandemic because she has Hashimoto disease, an autoimmune disorder that she knew put her at high risk for complications. She was right to be worried. Two months after contracting the infection in September 2022, the 42-year-old Nashville resident was diagnosed with...
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Researchers discover unique blood plasma protein patterns in patients with long COVID
by University of Western Ontario Credit: Pixabay/CC0 Public Domain Using advanced research techniques, including a form of artificial intelligence, a team of researchers has discovered unique patterns of blood plasma proteins in patients with suspected long COVID that could improve patient outcomes. This research, which used multiple state-of the-art technologies, was enabled by existing expertise and infrastructure through CHRI. It was...
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Long COVID not caused by COVID-19 immune inflammatory response, new research finds
by University of Bristol Ongoing symptoms at three months and associations with immune profiles. (A, B) The percentage of patients with mild (N=17), moderate (N=32), and severe (N=14) coronavirus disease-19 (COVID-19) who reported the indicated symptom (A) or number of symptoms (B) at three months are indicated with white, grey, and black bars, respectively. Statistics were calculated...
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Prolonged inflammation associated with long COVID restored to healthy levels within two years post-infection: Study
by Agency for Science, Technology and Research (A*STAR), Singapore A 12-month longitudinal systemic cytokine analysis of COVID-19 patients reveals a cluster of patients with persisting elevations of proinflammatory cytokines. Longitudinal plasma samples were collected across 5 time points up to 12 months post-illness onset from 78 COVID-19 patients. Concentrations of 45 immune mediators were quantified using a 45-plex...
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Novel drug could treat long COVID and prevent re-infection
by QIMR Berghofer Graphical overview of epigenetic reprograming in hamster bronchiolar epithelium and human CD14+ monocytes. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-39341-4 A new drug developed by QIMR Berghofer could transform the treatment of COVID-19 by potentially protecting against infection by any SARS-CoV-2 variant and reversing the persistent inflammation that is a major driver of debilitating long COVID....
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Similar symptoms, biological abnormalities underlie long COVID and chronic fatigue syndrome
by Brigham and Women’s Hospital Credit: Unsplash/CC0 Public Domain Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome are debilitating conditions with similar symptoms. Neither condition has diagnostic tests or treatments approved by the Food and Drug Administration (FDA) and each cost the United States billions of dollars each year in direct medical expenses and lost productivity. Doctors and researchers...
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New INSPIRE group data shows ‘long COVID’ not a single condition
by Rush University Medical Center INSPIRE is CDC- funded collaboration of eight major academic medical centers seeking to better understand the long-term effects of COVID. Credit: RUSH Production Group The latest data from the nationwide INSPIRE study assessing the long-term symptoms and outcomes of the COVID-19 virus in nearly 6000 participants identifies four clinically distinct symptom...