by UT Southwestern Medical Center UT Southwestern researchers (l-r) Farjana Fattah, Ph.D., Mitchell S. von Itzstein, M.D., David E. Gerber, M.D., and Kelly Kyle, B.S., discovered a drug that shows promise in treating non-small cell lung cancer with KRAS mutations. Credit: UT Southwestern Medical Center An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in...
Tag: <span>Lung cancer</span>
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Cambridge researchers develop urine test for early detection of lung cancer
Cambridge scientists have developed a urine test for early detection of lung cancer. The test, the first of its kind, detects ‘zombie’ cells that could indicate the first signs of the disease. Researchers hope that early detection, through the simple urine test, could enable earlier treatment interventions, significantly improving patient outcomes and prognosis. Around 36,600...
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Fibroblastic reticula cells can organize T cells in the fight against lung cancer
by Justin Jackson , Medical Xpress Graphical abstract. Credit: Cell (2024). DOI: 10.1016/j.cell.2024.10.042 Institute of Immunobiology-led research has made a significant breakthrough in understanding how the body combats lung cancer. Their study reveals that specific cells, known as fibroblastic reticular cells (FRCs), create environments within tumors that help protect and activate immune cells to fight the cancer...
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Gene activation linked to severity of a rare lung cancer
October 2, 2024by University of Cologne ERT expression and telomerase activity in pulmonary carcinoids. Credit: Journal of Clinical Oncology (2024). DOI: 10.1200/JCO.23.02708Pulmonary carcinoids are rare tumors of the lung with extremely different clinical courses. In many patients, they behave like benign tumors; surgical removal of the tumor leads to a complete cure. However, some patients...
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New drug combination shows promise for small cell lung cancer
September 30, 2024 by The Mount Sinai Hospital Researchers at the Icahn School of Medicine at Mount Sinai have made a promising breakthrough in the treatment of small cell lung cancer (SCLC). Their study, published in Science Advances and titled “ATR Inhibition Activates Cancer Cell cGAS/STING-Interferon Signaling and Promotes Anti-Tumor Immunity in Small Cell Lung...
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Combination treatment improves response to immunotherapy for lung cancer, mouse study shows
September 25, 2024 by The Francis Crick Institute Credit: Pixabay/CC0 Public DomainResearchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors. Their findings show that targeting tumors in different ways simultaneously might increase...
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Lung complications + rheumatoid arthritis increase risk for lung cancer
September 8, 2024 by Lori Solomon The risk for lung cancer is high in patients with rheumatoid arthritis (RA) and pulmonary complications, according to a study published online Sept. 3 in Modern Rheumatology. Shunsuke Mori, M.D., Ph.D., from the Kumamoto Saishun Medical Center in Koshi, Japan, and colleagues assessed the incidence and predictive factors of...
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Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection
August 5, 2024 by Liz Murphy, Massachusetts General Hospital Distribution of smoking duration (years), smoking intensity (cigarettes per day), and pack-year smoking history among SCCS participants diagnosed with lung cancer. SCCS, Southern Community Cohort Study. Credit: Journal of Clinical Oncology (2024). DOI: 10.1200/JCO.23.01780Early detection of lung cancer through low-dose computed tomography screening is one of...
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Detecting lung cancer early with sugar-sensing nanotech
JULY 1, 2024 by Australian Institute for Bioengineering and Nanotechnology (AIBN) A new nanodevice designed by AIBN researchers analyses sugars on the surface of cellular messenger particles to catch early signs of lung cancer. Credit: AIBN/UQFor such a common disease, lung cancer can be hard to spot. In the early stages you probably won’t even...
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‘Self-taught’ AI tool helps to diagnose and predict severity of common lung cancer
JUNE 11, 2024 by NYU Langone Health Credit: Unsplash/CC0 Public Domain A computer program based on data from nearly a half-million tissue images and powered by artificial intelligence can accurately diagnose cases of adenocarcinoma, the most common form of lung cancer, a new study shows. Researchers at NYU Langone Health’s Perlmutter Cancer Center and the...