by Massachusetts General Hospital Lung CA seen on CXR. Credit: James Heilman, MD/Wikipedia Lung cancer, the leading cause of cancer death, is usually diagnosed at a late stage when the survival rate is extremely low. Early-stage lung cancer is mostly asymptomatic, and low-dose spiral CT imaging, the current method for detecting early lung cancer lesions, isn’t...
AMERICAN COLLEGE OF SURGEONS IMAGE: IMPLEMENTATION OF A NOVEL, SINGLE-ENCOUNTER TELEMEDICINE LUNG CANCER SCREENING (SET-LCS) DURING COVID-19 PRESERVES ACCESS AMONG AFRICAN AMERICANS. CREDIT: AMERICAN COLLEGE OF SURGEONS Key takeaways Telemedicine screening preserved access to lung cancer screening during the COVID-19 pandemic for a safety net hospital’s large African American patient population. Despite the opportunity to...
Despite smoking’s well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called “never-smokers,” a study led by scientists at Washington University School of Medicine in St. Louis demonstrates new possibilities for treating these baffling tumors....
New research shows that the QL1101, structurally similar to an existing cancer drug, is a safe and effective alternative for lung cancer treatment. In 2018, lung cancer caused 1.8 million cancer deaths worldwide. It is the most common type of cancer, with non-small cell lung cancers (NSCLCs) accounting for 85% of lung cancers. Most recent lung cancer research focuses...
MEDICAL UNIVERSITY OF VIENNA Lung cancer has the highest mortality rate of all cancers, and treatment options are extremely limited, especially for patients with oncogenic mutations in the KRAS gene. A great deal of hope was invested in the licensing of immune checkpoint inhibitors, but the reality is that some patients respond very well to...
by Joe Dangor, Mayo Clinic Credit: Pixabay/CC0 Public Domain Research by investigators at Mayo Clinic Cancer Center suggests that physicians should screen patients with lung cancer for MET amplification/overexpression before determining a treatment strategy. Their findings are published in Cancer Discovery, a journal of the American Association for Cancer Research. “In our research, we found several...
by University of California, Irvine During lung cancer progression and the corresponding development of cachexia, circadian control of glucose production is disrupted, resulting in increased levels of glucose from the liver. These findings illustrate tissue-tissue crosstalk whereby a lung tumor can disrupt the circadian metabolism of a distal tissue, potentially for its own growth advantage. Credit:...
by Sarah Avery, Duke University School of Nursing Fig 1. CFH in EVs from CMT167 wild type vs. CFH knockout lung cancer cell lines. EVs were isolated from cell line conditioned media and 7.5 μg protein were western blotted and probed with GT103 and an anti-human IgG-HRP, then stripped and probed with anti-CD63 (SBI Biosystems) and...
by Dennis Thompson An immunotherapy drug is the first to significantly reduce the risk of cancer recurrence or death in people with early-stage lung cancer, researchers report. Atezolizumab reduced by 34% the risk of disease recurrence or death in a certain group of people with stage II to IIIA non-small cell lung cancer —those whose tumors carry a protein...
KRAS is one of the most common drivers of cancer and is involved in one-third of non-small cell lung cancers. It’s proved an elusive target thanks to its smooth structure and biochemistry. And although new inhibitors are demonstrating some success against one type of KRAS, new paths are needed. A study from University of Michigan...
