Patients with lung disease could find relief by breathing in messenger RNA molecules MASSACHUSETTS INSTITUTE OF TECHNOLOGY Messenger RNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases. The biggest obstacle to this approach so far has been finding safe and efficient ways to deliver mRNA molecules to...
Tag: <span>Lung disease</span>
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Single transplantation of therapeutic macrophages improves rare lung disease in mice
Hereditary pulmonary alveolar proteinosis (herPAP) is a rare disease characterized by the slow build-up of lipo-protein material in the lungs due to the failure of highly specialized cells called macrophages, which usually eat away this material from the pulmonary air-space. On August 9 in the journal Stem Cell Reports, researchers in Germany demonstrate that a single...
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High prevalence of restrictive lung disease in people with type 2 diabetes
July 12, 2018, Deutsches Zentrum fuer Diabetesforschung DZD Breathlessness and conditions of restrictive lung disease (RLD), such as pulmonary fibrosis, may be a late complication of type 2 diabetes. These are the key findings of a joint study undertaken by researchers from the German Center for Diabetes Research (DZD) and the German Center for Lung...
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Synthetic surfactant could ease breathing for patients with lung disease and injury
July 9, 2018, Lawson Health Research Institute Human lungs are coated with a substance called surfactant which allows us to breathe easily. When lung surfactant is missing or depleted, which can happen with premature birth or lung injury, breathing becomes difficult. In a collaborative study between Lawson Health Research Institute and Stanford University, scientists have developed and tested a new...
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Study identifies new molecular target for treating deadly lung disease IPF
In this microscopic photo of tissue from mouse lung with idiopathic pulmonary fibrosis (IPF), extensive fibrosis and collagen deposits (shown in red) have extensively infiltrated the tissue. Researchers at Cincinnati Children’s report Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target...
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Scientists discover new gene associated with debilitating lung disease
Health scientists at the University of Leicester and University of Nottingham have heralded the discovery of a gene associated with lung fibrosis as ‘a potential new avenue of treatment for further research into this terrible disease.’ The breakthrough is announced in a paper published in The Lancet Respiratory Medicine. Idiopathic Pulmonary Fibrosis (IPF) is a debilitating lung disease,...
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Drug to tackle lung scarring shows promise
People with a lung scarring condition that leaves them fighting for breath could be helped by a new medication, research suggests. Results from an early stage clinical trial show that the new drug has no serious side effects and was well tolerated by patients with the condition, called Idiopathic Pulmonary Fibrosis. New therapy The findings...