by Medical University of South Carolina Immunofluorescence images showing healthy (left) and scleroderma (right) lung. The scleroderma lung shows reduced levels of Cathepsin L (green) and increased levels of fibroblast activation marker (red). Image courtesy of Joe Mouawad, Medical University of South Carolina. Credit: Joe Mouawad, Medical University of South Carolina Much of the research...
CEDARS-SINAI MEDICAL CENTER Investigators from the Women’s Guild Lung Institute at Cedars-Sinai have discovered that zinc, a common mineral, may reverse lung damage and improve survival for patients with a deadly age-related condition known as idiopathic pulmonary fibrosis (IPF). Their findings, published in The Journal of Clinical Investigation, have the potential to change the landscape of treatment for...
SOCIETY OF NUCLEAR MEDICINE AND MOLECULAR IMAGING IMAGE: A) Axial CT images through the mouse lungs at 7 and 14 days after intratracheal administration of bleomycin or saline (as a control), demonstrating increased lung fibrosis in the bleomycin group (white arrows). (B) CT attenuation histograms in Hounsfield units (HU) after lung segmentation demonstrate increased attenuation...
Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism. Jaroslaw Zmijewski and Victor Thannickal. Credit: UAB This novel finding, reported in the journal Nature Medicine, is important because, despite significant advances to reveal the pathological mechanisms of persistent fibrosis,...
A team of scientists from the UNC School of Medicine and North Carolina State University (NCSU) has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis — often-fatal conditions that affect tens of millions of Americans. In...
