September 3, 2024 by Maria Fernanda Ziegler, FAPESP Lung autopsy tissue infected by SARS-CoV-2 with endothelial cells (red), active inflammasome (green) and SARS-CoV-2 RNA (pink), showing that the virus was replicating. Credit: Keyla de SáAccording to an article published in the journal PLOS Pathogens, severe COVID-19 patients can be divided into two distinct groups: those...
by Mallory Locklear, Yale University Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111797 Yale researchers have identified a possible driver of the persistent inflammation that causes irreversible lung damage in patients with cystic fibrosis, a genetic disorder that impairs breathing and digestion. In a new study, they uncover how a type of white blood cell called a...
UNIVERSITY OF MÜNSTER IMAGE: PLATELETS (RED) INTERACTING WITH REGULATORY T CELLS (YELLOW) IN THE BACTERIALLY INFLAMED LUNG TISSUE OF A MOUSE. RESEARCHERS EXAMINED THE LIVING TISSUE USING CONFOCAL FLUORESCENCE MICROSCOPY. CREDIT: ROSSAINT ET AL./JEXPMED 2021 Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause...
Scientists at BioAegis in New Jersey are developing a drug version of the protein gelsolin It exists in the human body and helps combat life-threatening inflammation like that seen in patients with pneumonia from coronavirus Their small trial in mild pneumonia patients found that it helped them recover better and faster than those given standard...
Tests using mice employed an experimental drug that stimulates a specific type of nicotinic receptor in immune cells; researchers attested the reversion of the inflammation condition It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of...
