by Ecole Polytechnique Federale de Lausanne gulation factor XII (FXII), and the mice without the enzyme had a highly reduced risk of thrombosis without bleeding side-effects. The discovery triggered a race for FXII inhibitors. The Laboratory of Therapeutic Proteins and Peptides of Professor Christian Heinis at EPFL has now developed the first synthetic inhibitor of...
Tag: <span>Lungs</span>
Drug-induced interstitial lung disease in breast cancer patients
A lesson we should learn from multi-disciplinary integration Announcing a new article publication for BIO Integration journal. In this case report the authors Zijun Zhao, Zhanghai He, Hongyan Huang, Jiewen Chen, Shishi He, Ailifeire Yilihamu and Yan Nie from Sun Yat-sen University, Guangzhou, China consider drug-induced interstitial lung disease in breast cancer patients. Taxanes represented...
New system uses X-ray images of patients’ lungs to diagnose COVID-19
Reviewed by James Ives, M.Psych. (Editor) Researchers from the Department of Computer Architecture and Technology at the University of Seville’s School of Computer Engineering (ETSII) are working on a system that uses X-ray images of patients’ lungs to help diagnose COVID-19. This system uses deep learning to train a neural network model that can distinguish...
Taking cholesterol-lowering drug could reduce severity of coronavirus to the level of the common cold, study claims
By HARRIET ALEXANDER FOR DAILYMAIL.COM Cholesterol-lowering drug Fenofibrate (Tricor) is providing a glimmer of hope Scientists in New York and Jerusalem believe the drug could help treat COVID The drug could reduce symptoms so that COVID-19 is no worse than a common cold, the study found Two scientists researching a potential treatment for coronavirus believe...
Exhaled biomarkers can reveal lung disease
Specialized nanoparticles create a ‘breath signal’ that could be used to diagnose pneumonia and other infectious or genetic diseases MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice,...
Experts strongly recommend varenicline over the patch for adult smokers hoping to quit
ATS publishes new practice guideline on tobacco dependence treatment AMERICAN THORACIC SOCIETY ATS PUBLISHES NEW CLINICAL PRACTICE GUIDELINE ON TREATING TOBACCO DEPENDENCE IN ADULTS. view more CREDIT: ATS July 15, 2020 – Smoking cessation initiatives notwithstanding, along with provocative public health campaigns and clinical guidance, quitting tobacco has remained elusive for many smokers. The American...
World-first technology breathes new life into cystic fibrosis detection and treatment
by Monash University Regional fractional expansion of the lung since the beginning of the breath is characterized as a fraction of the XV voxel. Coronal slices of the expansion at peak inspiration are shown for (a) a β-ENaC mouse (M3) and (b) a healthy littermate (M9). Credit: Monash University World-first research led by Monash University...
Not as gross as it sounds: predicting how bacteria in mucus affect human health
Inhale, exhale. Humans breathe between 17,000 to 23,000 times a day, on average. But for more than 70,000 children and young adults around the world, taking a breath can be a struggle because of a rare disease, cystic fibrosis. A gene that normally triggers a certain protein to move chloride, found in salt, to cell...
Stem Cell Exhaustion in the Aging Lung
Stem cell activity declines with age throughout the body. In some cases this is because stem cellsbecome less active in response to changes in the signaling environment. In other cases, the cells are damaged or the populations greatly reduced. The consequence of this decline is that fewer daughter somatic cells are produced to make up...
Physicians give first comprehensive review of COVID-19’s effects outside the lung
by Columbia University Irving Medical Center After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Aakriti Gupta, MD, realized that this was much more than a respiratory disease. “I was on the front lines right from the beginning. I observed that patients were...