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Targeting type of B cell could reduce lupus disease, study suggests
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Targeting type of B cell could reduce lupus disease, study suggests

by University of Pittsburgh Credit: Pixabay/CC0 Public Domain A group of University of Pittsburgh researchers has given new meaning to “knowing your ABCs.” In a new study, published in the Journal of Experimental Medicine, the team showed that a type of immune cell called age-associated B cells, or ABCs, are important drivers of lupus and that targeting these...

How changing gut microbiota can affect lupus disease activity in mice
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How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State University Figure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter from mice harboring SFB or control mice and sacrificed at 30-weeks of age and subjected to biochemical analysis. (A) Serum blood urea nitrogen (BUN). (B) Kidney disease...