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Fundamental feature of aggressive lymphomas discovered
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Fundamental feature of aggressive lymphomas discovered

by  University of Southampton The crystal structure of a fragment of a B-cell receptor from an aggressive lymphoma. The receptor is modified by carbohydrate, termed a glycan, shown in green sticks. The protein chains are depicted as a tube with the loops around the glycan coloured. Credit: University of Southampton Research led by the University of Southampton...

Scientists discover a key genetic driver of lymphomas
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Scientists discover a key genetic driver of lymphomas

by  Weill Cornell Medical College Histone H1 (fragment shown here in gray) binds and condenses DNA to repress gene activity. Mutations in histone H1 (highlighted in red) have been identified at high frequency in many hematological malignancies. Credit: Weill Cornell Medical College Mutations in proteins called histone H1, which help package DNA in chromosomes, are a...