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How Type 2 Diabetes is Similar to Mad Cow Disease

A recent study showed that misfolded protein aggregates in pancreatic tissue can act as seeds to spread type 2 diabetes processes, similar to the self-propagation of infectious prions. A large protein aggregate (green) forms in a pancreatic islet (red) from a transgenic mouse injected with extract containing misfolded IAPP (1). Some of the symptoms of...