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Selenium-based compounds target SARS-CoV-2 with unusual inhibition mechanism of its main protease
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Selenium-based compounds target SARS-CoV-2 with unusual inhibition mechanism of its main protease

Scientists have discovered a new mechanism of inhibiting a critical enzyme of the SARS-CoV-2 virus, demonstrating the on-target engagement of novel selenium based compounds. An international team of researchers led by the University of Liverpool has shown that a Selenium-based drug molecule called ebselen and several derivative compounds can halt SARS-CoV-2 replication by targeting its main protease...