Analysis using CRISPR gene-editing technology suggests that drugs’ mechanism of action are misunderstood. Heidi Ledford Many experimental cancer drugs might be succeeding in unintended ways, finds a study that used CRISPR–Cas9 gene editing to investigate how such drugs interact with malignant cells. An analysis of ten drugs — including seven now in clinical trials —...
Tag: <span>maligant</span>
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Seawater bacteria provides leads to fight melanoma
Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads for an entirely new way to treat the disease. In melanoma, cancer cells form in melanocytes, the cells that color the skin....