Caltech scientists have developed a method driven by machine learning that allows them to accurately measure the mass of individual particles and molecules using complex nanoscale devices. The new technique opens the possibility of using a variety of devices for the measurement of mass and, therefore, the identification of proteins and could pave the way...
Tag: <span>mass spectrometry</span>
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Mass spectrometry to detect key markers of Alzheimer’s
by Skolkovo Institute of Science and Technology Experiment scheme and the results of the study: transgenic mice with Alzheimer’s disease-like beta-amyloid plaques in the brain. The degree of isomerization of beta-amyloid peptides (vertically) is determined by the intensity of the mass spectrometric signal (horizontally). The results obtained for the human brain (green dot) are consistent with...
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Seeing lipids more deeply with mass spectrometry
TOKYO MEDICAL AND DENTAL UNIVERSITY VIDEO: SEEING LIPIDS MORE DEEPLY WITH MASS SPECTROMETRY CREDIT: PROFESSOR TAKEHIKO SASAKI, TMDU The development of new scientific ways to see more deeply into the building blocks of nature on a cellular level has led to the some of the greatest advances in medicine over the last century. Now, new...
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New mass spectrometry-based technique provides insights into the evolution of the brain
by Ruhr-Universitaet-Bochum Fig. 1. Systematic screening for epigenetic marks showing differential levels between mouse and human bIPs. (A) A scheme of the experimental design used to compare the transcriptomes and epigenomes of mouse and human BPs. (B and C) Purification of Tbr2+ bIPs in developing mouse and human cortex. Representative images of cell suspensions from mouse...