by Skolkovo Institute of Science and Technology Experiment scheme and the results of the study: transgenic mice with Alzheimer’s disease-like beta-amyloid plaques in the brain. The degree of isomerization of beta-amyloid peptides (vertically) is determined by the intensity of the mass spectrometric signal (horizontally). The results obtained for the human brain (green dot) are consistent with...
TOKYO MEDICAL AND DENTAL UNIVERSITY VIDEO: SEEING LIPIDS MORE DEEPLY WITH MASS SPECTROMETRY CREDIT: PROFESSOR TAKEHIKO SASAKI, TMDU The development of new scientific ways to see more deeply into the building blocks of nature on a cellular level has led to the some of the greatest advances in medicine over the last century. Now, new...
by Ruhr-Universitaet-Bochum Fig. 1. Systematic screening for epigenetic marks showing differential levels between mouse and human bIPs. (A) A scheme of the experimental design used to compare the transcriptomes and epigenomes of mouse and human BPs. (B and C) Purification of Tbr2+ bIPs in developing mouse and human cortex. Representative images of cell suspensions from mouse...
