UMEA UNIVERSITY ILLUSTRATION OF HOW THE PROTEIN SMAD7 ENHANCES THE DEVELOPMENT OF TUMORS BY REGULATING THE GENE EXPRESSION OF HDAC6 AND C-JUN. view more CREDIT: KEMAL AVICAN An increased awareness on a molecular level of what mechanisms prostate cancer cells use to become mobile and start spreading may in the long run provide new opportunities...
by Tel Aviv University Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising. A new Tel Aviv University study finds that melanoma brain metastasis occurs when tumor cells “hijack” an inflammatory pathway in the brain. Blocking this pathway...
Combination immunotherapy shrank melanoma that has spread to the brain in more than half of the patients in a clinical trial reported in the New England Journal of Medicine led by an investigator at The University of Texas MD Anderson Cancer Center. Hussein Tawbi, M.D., Ph.D. Credit: MD Anderson Cancer Center Of 94 patients in the single-arm study combining...
CHICAGO – High response rates to a pair of combination therapies point to potentially new options for a group of metastatic melanoma patients who have been largely left out of recent treatment progress – those whose disease has spread to the brain. A combination regimen of two immunotherapies and another of two targeted therapies each...
