by QIMR Berghofer Medical Research Institute Age-standardized melanoma incidence from 1982 through 2018 in the U.S. White, Queensland, and Scotland populations. Joinpoint regression models for in situ and invasive melanoma: A) Queensland, B) United States (U.S.) White, C) Scotland populations, and D) in situ to invasive melanoma incidence rate ratios. ASR = age-standardized rate (U.S....
SANFORD BURNHAM PREBYS IMAGE: ZE’EV RONAI, PH.D. CREDIT: SANFORD BURNHAM PREBYS LA JOLLA, CALIF. – Sept 01, 2022 –Researchers at Sanford Burnham Prebys, led by Ze’ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, these findings could lead to...
by Julia Moióli, FAPESP Researchers at the University of São Paulo showed, through experiments on animals and genetically modified cells, that this type of cancer advances more slowly when the light-sensitive molecule known as melanopsin is deactivated. The discovery could point to novel therapeutic strategies. Credit: Wikimedia Commons Melanopsin (OPN4) is a light-sensing protein found in...
by Alex Osiadacz Credit: Wikimedia Commons/National Cancer Institute Melanoma is a type of skin cancer that develops in cells that produce your skin’s pigment. Regular skin checks can help you identify the warning signs and differentiate melanoma from noncancerous skin formations, according to the American Academy of Dermatology. Moles are a common skin growth, and...
Cancers in humans have all sorts of ways to survive and thrive: Cells and tumors use devious means to deflect, deceive, and evade detection by our bodies’ immune systems. Take how they fend off anti-cancer vaccines, for example. Cancer cells in the body, whether singularly or consolidated, essentially cloak themselves through chemical secretions to remain...
by Columbia University Irving Medical Center Credit: Pixabay/CC0 Public Domain Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma. Although new immunotherapies are effective in some patients with melanoma brain metastases, little is known about the reasons for melanoma’s spread to the brain...
by University of Nottingham Rationale of the ELK1-GO membrane reduction process and application. Illustration depicting a). exposure of 70% ethanol to an ELK1-GO complex comprising stacks of GO. b). ELK1-GO complexes form multi-layered ELK1-GO membranes, which are co-assembled at the interface of a GO solution and an ELK1 solution. c). Ethanol molecules penetrate the ELK1...
by UC Davis Microscopic image of melanocyte cells that produce skin and eye pigment. Credit: UC Davis A new UC Davis-led study sheds light on cell type-specific biomarkers, or signs, of melanoma. The research was recently published in the Journal of Investigative Dermatology. Melanoma, the deadliest of the common skin cancers, is curable with early diagnosis and treatment. However,...
by Jason Howland, Mayo Clinic Credit: Wikimedia Commons/National Cancer Institute Melanoma is the most serious type of skin cancer. It develops in the cells that produce the pigment in your skin that gives it color. It most often occurs on skin that is exposed to the sun, but can develop in your eyes and, rarely, inside...
HARVARD MEDICAL SCHOOL At a glance: Researchers have created spatial maps of melanoma that show how individual cells interact as the cancer progresses The maps reveal details of how melanoma suppresses the immune system as it takes over The team is building the maps into a melanoma atlas that could help improve diagnosis and treatment...
