by University of Southern California Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C. In studies on mice, researchers found that the combination delayed tumor progression in multiple mouse models of colorectal cancer;...
Tag: <span>MELANOMA</span>
Immunotherapy before surgery could advance care of an aggressive form of skin cancer
In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery. In patients whose tumors respond, this treatment...
Vitamin D dials down the aggression in melanoma cells
CANCER RESEARCH UK Vitamin D influences the behaviour of melanoma cells in the lab by making them less aggressive, Cancer Research UK scientists have found. The researchers from the University of Leeds discovered that vitamin D influences the behaviour of a signalling pathway within melanoma cells, which slowed down their growth and stopped them spreading...
Bariatric surgery linked to reduced risk for skin cancer
(HealthDay)—For individuals with obesity, bariatric surgery is associated with a reduced risk for skin cancer, including melanoma, according to a study published online Oct. 30 in JAMA Dermatology. Magdalena Taube, Ph.D., from the University of Gothenburg in Sweden, and colleagues examined the correlation of bariatric surgery with skin cancer and melanoma incidence in the Swedish...
CNIO researchers assess melanoma progression with a new liquid biopsy technique
CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) When the surgeon surgically removes a melanoma, some patients are said to be ‘cancer-free’ and they do not get additional treatment. However, should the fluid obtained in the drainage implanted after surgery be tested using the liquid biopsy technique rather than be disposed of as medical waste, the test might predict the high or...
Physical combination multiplies melanoma risk
The risk of developing melanoma is significantly multiplied for people who have red hair and more than 20 large moles, University of Queensland researchers have found. People with these physical traits have a one in four chance of developing the disease in their lifetime. The study also showed that people without red hair, but who...
Low-cost ‘cancer probe’ could spot deadly melanoma early
Optical probe designed for preliminary screening for skin cancer designed at UBC Credit: Lou Corpuz-Bosshart Melanoma, the deadliest form of skin cancer, is diagnosed in more than 130,000 people globally every year. Now, work is being done on a tool to help in its early detection: a simple, compact laser probe that can distinguish between...
Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients
Among melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut microbiome diversity and better response to treatment, according to data presented during a media preview of the AACR Annual Meeting 2019, to be held March 29-April 3 in Atlanta. “We found that diet and supplements appear to have...
New PET probe could improve detection of primary and metastatic melanoma
Sample images of a melanoma patient. (A) Maximum-intensity-projection PET images at 10 and 60 minutes after 18F-P3BZA injection and at 60 minutes after 18F-FDG injection. (B) Transverse images of primary melanoma (red arrow), lymph node metastasis (yellow arrow), and bone metastasis (blue arrow). (C) H&E (upper part) and immunohistochemistry (lower part) images of primary melanoma. Credit: Xiaowei Ma, Shengjun Wang et al., Xijing Hospital,...
Christmas berry’ plant compound could fight Uveal melanoma
A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer THOMAS JEFFERSON UNIVERSITY PHILADELPHIA–Doctors diagnose about 2000 adults with uveal melanoma, a cancer of the eye, every year. In half of cases, the disease metastasizes to the liver. For these patients...