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Biophysicists reveal how optogenetic tool works
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Biophysicists reveal how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state. The discovery provides a description of the mechanism behind the light-driven sodium ion transfer across the cell membrane. The paper came out in Nature Communications. KR2 is a member of a very large...

A fidget spinner-like device for speedy detection of UTIs in urine
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A fidget spinner-like device for speedy detection of UTIs in urine

The Dx-FS as a POCT device for low-resource settings. a, In developing countries such as India, healthcare is classified into three levels: primary, secondary and tertiary care. Although secondary and tertiary care centres are equipped with laboratories for UTI screening, the same does not exist in primary care centres34,35. Patients seeking intervention with symptoms of...

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Arteries respond in opposite ways for males and females – pharmaceutical

CREDIT: COPYRIGHT UC REGENTS/UC DAVIS HEALTH A protein known to expand blood vessels — key to controlling conditions like high blood pressure — actually has different functions in males and females, new UC Davis Health research shows. Conducted using arterial cells from mice, the study is the first to identify sex-based distinctions in how the...

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Stabilizing dysferlin-deficient muscle cell membrane improves muscle function

In experimental model of LGMD2B, vamorolone improves and prednisolone worsens myofiber repair CHILDREN’S NATIONAL HEALTH SYSTEM WASHINGTON-(Aug. 27, 2018)-Healthy muscle cells rely on the protein dysferlin to properly repair the sarcolemmal membrane, a thin specialized membrane that serves a vital role in ensuring that muscle fibers are strong enough and have the necessary resources to...

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