Medscape Medical News > Features Marilynn Larkin August 14, 2024 Dry fasting, the practice of going without food and water, has enthusiastic advocates on TikTok, X, YouTube, and other social media platforms. Devotees claim a wide range of health effects, but medical professionals advise caution to ensure that the practice does more good than harm,...
Tag: <span>metabolic disorders</span>
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Researchers identify the target of immune attacks on liver cells in metabolic disorders
by Weill Cornell Medical College Illustration of human liver anatomy. Credit: Shutterstock When fat accumulates in the liver, the immune system may assault the organ. A new study from Weill Cornell Medicine researchers identifies the molecule that trips these defenses, a discovery that helps to explain the dynamics underlying liver damage that can accompany type...
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Bits of genetic material called microRNAs may drive metabolic disorders
by Jacob Shea, University of California – Berkeley The miR-128-1 microRNA, a tiny snippet of regulatory RNA emanating from the ‘dark matter’ of the genome previously thought to be junk DNA, controls energy metabolism and contributes to metabolic diseases such as obesity and type 2 diabetes. It is linked to human evolutionary selection for survival of...
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Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer
by Chinese Academy of Sciences Despite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to effective treatment of lung cancer. How do lung cancer cells adapt to targeted therapy? What is the molecular basis of such adaptive behavior? Can this adaptive response be memorized by cancer cells? If so,...
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Is Cancer a Metabolic Disorder?
By Samuel Mckenzie, BSc Reviewed by Dr. Jennifer Logan, MD, MPH Errors with the metabolism of cells can cause a multitude of different cancers. The metabolic mechanisms in cancerous cells can be forcibly hijacked to further support the cancerous phenotype of these cells. Fortunately, the metabolism of cancerous cells can be manipulated to provide therapeutic treatment for these cancers....
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How does your brain take out the trash?
By Tim Newman Fact checked by Gianna D’Emilio In this Spotlight, we introduce the glymphatic system: the brain’s dedicated waste clearance system. Now implicated in various conditions, it is high time that we became acquainted. Many of us are relatively familiar with the lymphatic system; it performs a number of roles, one of which is...
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Three easy measures to predict metabolic syndrome in elderly
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS New Rochelle, NY, April 2, 2019–A new study found a surprisingly high rate of metabolic syndrome among individuals aged 60-100 years. Three easy-to-measure anthropometric indicators were predictive of metabolic syndrome in both men and women and could be useful for indicating the need for preventive care and further testing,...
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Chronic diseases driven by metabolic dysfunction
New model suggests natural healing cycle becomes blocked by cellular miscommunication, allowing conditions like cancer, diabetes and some neurological disorders to persist; a small but dramatic autism trial offers evidence UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: THIS IS A FALSE-COLOR TRANSMISSION ELECTRON MICROGRAPH OF A MITOCHONDRION INSIDE A CELL Much of modern Western medicine is...
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Mysterious protein-folding molecule could trigger metabolic disorders
The cell’s response to unfolded or misfolded proteins could be a cause, rather than a consequence, of metabolic disorders, report researchers at the Medical University of South Carolina (MUSC) in an article published online ahead of print on September 4, 2017 by Nature Structural & Molecular Biology. The researchers identified a little-known molecule as the trigger...