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Inhibiting key metabolic enzyme shows promise against melanoma
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Inhibiting key metabolic enzyme shows promise against melanoma

SANFORD BURNHAM PREBYS IMAGE: ZE’EV RONAI, PH.D. CREDIT: SANFORD BURNHAM PREBYS LA JOLLA, CALIF. – Sept 01, 2022 –Researchers at Sanford Burnham Prebys, led by Ze’ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, these findings could lead to...

Glioblastoma study discovers protective role of metabolic enzyme, revealing a novel therapeutic target
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Glioblastoma study discovers protective role of metabolic enzyme, revealing a novel therapeutic target

UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER IMAGE: FROM LEFT TO RIGHT: FRANCESCA PUCA, PH.D., ANDREA VIALE, M.D., AND GIULIO DRAETTA, M.D., PH.D. CREDIT: MD ANDERSON CANCER CENTER HOUSTON – Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM)....