Scientists found a previously unknown link between mitochondria and kidney disease, identifying a receptor that causes kidney dysfunction when suppressed, according to a study published in Proceedings of the National Academy of Sciences. The receptor—estrogen-related receptor gamma (ERRγ)—regulates mitochondrial metabolism, and was also found in unusually low levels in patients with chronic kidney disease, pointing to its...
Tag: <span>metabolism</span>
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Inhibiting metabolism found to be effective in treating aggressive form of lung cancer
Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung. The two drugs, MLN128 and CB-839, individually target the metabolism of key nutrients glucose and glutamine, respectively, prohibiting cancer from switching metabolic gears between...
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Your bones affect your appetite—and your metabolism
Your skeleton is much more than the structure supporting your muscles and other tissues. It produces hormones, too. And Mathieu Ferron knows a lot about it. The researcher at the Montreal Clinical Research Institute (IRCM) and professor at Université de Montréal’s Faculty of Medicine has spent the last decade studying a hormone called osteocalcin. Produced...