by Ingrid Fadelli, Medical Xpress Images showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a super resolution image of microglia caught in the act of proliferation, shown here is microglia in vivo in cytokinesis phase post ATV:TREM2 dosing; cell nuclei...
by Pat Harriman, University of California, Irvine Single nucleus RNAseq of mouse and human R6/2 and HD samples. a Illustration of workflow used for this study. After frozen tissue is microdissected from the Cingulate, Caudate, and nucleus Accumbens from 66 samples from 29 human donors (3 grade I, 4 grade II, 4 grade III, 3 grade IV, 5...
Faith GeigerMon, November 7, 2022 at 3:00 AM woman holding plate of toast and checking watch It’s impossible to overstate the importance of a healthy breakfast when it comes to weight loss. The right breakfast will give you the energy you need to take on the day, smash your workouts, and burn calories in order to kick...
by Kerstin Henriksson, Uppsala University Overview of the study and exploration of the proteomics dataset. a) Schematic overview of tissue samples. Doughnut charts show the distribution of CTRL, PD and T2D subjects. The two outer circles show the fraction of subjects belonging to the merged groups of CTRL+PD and PD+T2D. b) Venn diagram that summarizes...
by Aarhus University Credit: Pixabay/CC0 Public Domain Can you eat your way out of a kidney disease? Perhaps you can—according to a new study from Aarhus University. In the study, Associate Professor Markus Rinschen from Aarhus Institute of Advanced Studies and Department of Biomedicine has shown that the intake of the amino acid lysine, an over-the-counter...
by Perelman School of Medicine at the University of Pennsylvania Credit: Pixabay/CC0 Public Domain Liver cancer’s rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania. In...
by Texas A&M University Shaodong Guo, Ph.D., in his laboratory. Credit: Texas A&M AgriLife photo Estrogen may protect diabetes patients from cardiomyopathy, according to research led by a Texas A&M AgriLife scientist and published in the June issue of Circulation: Heart Failure. The study showed that severe insulin resistance in the heart causes cardiomyopathy and death in male mice....
by University of Eastern Finland Figure 1. The association of physical activity (PA) changes with glucose and insulin concentrations, insulin sensitivity, and insulin secretion in 5867 participants without diabetes at baseline, subjected to oral glucose tolerance tests both at baseline and follow-up visits. The effect sizes (β, SE) are given as the standardized mean differences...
by Universität Leipzig Philipp Rabe and Aenne-Dorothea Liebing, both study authors, working with cell cultures. Credit: Dr. Claudia Stäubert Cancer cells show unchecked rapid growth beyond tissue boundaries that is no longer stopped by normal control mechanisms. Due to this rapid growth, the metabolism of cancer cells is altered compared to that of cells that...
OHIO STATE UNIVERSITY COLUMBUS, Ohio – A new study in mice shows transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack, an encouraging finding for scientists who hope to apply the so-called “good” fat’s beneficial properties to drugs that can help prevent health problems. In the study, transplanting brown fat...
