Tag: <span>Metabolome</span>

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Unique metabolic markers detect over 50% of children affected by autism spectrum disorder

New findings from the Children’s Autism Metabolome Project (CAMP) Study, a 1,102 subject study of the metabolism of children with ASD, published in Autism Research Madison, WI (June 18, 2020): In a paper published online this week in Autism Research, scientists at NeuroPointDX, a division of Stemina Biomarker Discovery, Inc., in collaboration with researchers at...

New biomarker could flag tumors that are sensitive to common diabetes drug
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New biomarker could flag tumors that are sensitive to common diabetes drug

GRAND RAPIDS, Mich. (May 19, 2020) — A newly identified biomarker could help scientists pinpoint which cancers are vulnerable to treatment with biguanides, a common class of medications used to control blood sugar in Type 2 diabetes. Biguanides, particularly a medication called metformin, have long been of interest to cancer researchers because of their ability...

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Study finds evidence for existence of elusive ‘metabolon’

UNIVERSITY PARK, Pa. — For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or “metabolons,” in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers at Penn State, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular...

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Metabolomic Profiling for Disease Diagnosis

The Human Metabolome Database presently lists over 114,000 molecules. Each cell type, tissue or organ has a particular metabolomic fingerprint, unique due to the number and type of certain metabolites that are found there. Unexpected amounts or types of metabolites may imply a current or impending health issue. Christoph Burgstedt | Shutterstock While genomics and...