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Novel liquid metal nanoparticles for cancer photoimmunotherapy
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Novel liquid metal nanoparticles for cancer photoimmunotherapy

JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY IMAGE: A VERSATILE LIQUID METAL (LM) GALLIUM-INDIUM ALLOY HAS BEEN USED TO DEVELOP A NOVEL LM NANOPARTICLE THAT HARBORS AN IMMUNOMODULANT AND AN IMMUNE CHECKPOINT INHIBITOR, ANTI-PD-L1. UPON IRRADIATION BY NEAR INFRA-RED LIGHT, ANTI-PD-L1 SPECIFICALLY BINDS TO THE CANCER CELL, WHILE IMMUNOSTIMULANTS ACTIVATE T AND DENDRITIC CELLS. THIS...