by University of Gothenburg Figure 1. Credit: DOI: 10.1016/j.ajpath.2021.07.009 For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divides into...
Scientists discovered a genetic factor that determines whether ageing prostate cancer cells either die or become more aggressive. This finding provides important information for personalised therapy of patients. Aging tumour cells stop proliferating. This cell ageing process is called senescence. In cancer therapy, it is deliberately induced with drugs to slow down tumour growth. However,...
UMEA UNIVERSITY ILLUSTRATION OF HOW THE PROTEIN SMAD7 ENHANCES THE DEVELOPMENT OF TUMORS BY REGULATING THE GENE EXPRESSION OF HDAC6 AND C-JUN. view more CREDIT: KEMAL AVICAN An increased awareness on a molecular level of what mechanisms prostate cancer cells use to become mobile and start spreading may in the long run provide new opportunities...
University of Chicago Medicine investigators slow metastasis of colon cancer by ‘locking up’ cancer cells UNIVERSITY OF CHICAGO MEDICAL CENTER When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths. University of Chicago Medicine investigators...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Researchers at the IRCM, IRIC and University of Cambridge work together to reveal a mechanism involved in the formation of metastases. The 3D structure of the ELMO / DOCK2 complex, an important molecular machine that plays a crucial role in...
Researchers at the University of East Anglia and the University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives. Current treatment is grueling, with outdated chemotherapy cocktails and limb amputation. But despite all of this, the five-year survival rate is poor at just...
by Bob Yirka , Medical Xpress A team of researchers from Stanford University in the U.S. and Southern University of Science and Technology in China has found evidence that suggests metastasis of cancerous tumors may get its start much earlier than previously thought. In their paper published in the journal Nature Genetics, the group describes...
Combination immunotherapy shrank melanoma that has spread to the brain in more than half of the patients in a clinical trial reported in the New England Journal of Medicine led by an investigator at The University of Texas MD Anderson Cancer Center. Hussein Tawbi, M.D., Ph.D. Credit: MD Anderson Cancer Center Of 94 patients in the single-arm study combining...
