WINSTON-SALEM, N.C. – June 4, 2020 – Among people who have the most common type of lung cancer, up to 40% develop metastatic brain tumors, with an average survival time of less than six months. But why non-small-cell lung cancer so often spreads to the brain has been poorly understood. Now scientists at Wake Forest...
Tag: <span>metastasis</span>
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Study suggests metastasis gets its start much earlier than thought
by Bob Yirka , Medical Xpress A team of researchers from Stanford University in the U.S. and Southern University of Science and Technology in China has found evidence that suggests metastasis of cancerous tumors may get its start much earlier than previously thought. In their paper published in the journal Nature Genetics, the group describes...
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NANOPARTICLES ENTER LIVING CELLS TO GATHER CANCER CLUES
A new imaging technique sends nanoparticles into living cells to reveal important information about cell structure—including how tumor cells physically change as they form a tumor.A new imaging technique sends nanoparticles into living cells to reveal important information about cell structure—including how tumor cells physically change as they form a tumor.A new imaging technique sends...
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Preventing metastasis by stopping cancer cells from making fat
by Université catholique de Louvain Olivier Feron, a researcher at the University of Louvain (UCLouvain) Institute of Experimental and Clinical Research, seeks to understand how metastases form from a tumor. He previously demonstrated that the most aggressive cancer cells use significant amounts of lipids as energy sources. Now, Prof. Feron has discovered that cancer cells...
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Researchers Halt Spread of Breast Cancer by Blocking Metastasis-Promoting Enzyme
This news or article is intended for readers with certain scientific or professional knowledge in the field. Findings in Mice Point to New Approach That May Help Make Some Metastatic Breast Cancers Susceptible to Immunotherapy. In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found...
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Study unveils the intricate way two proteins interact to promote cell movement, metastasis
Posted Today When cells in our bodies need to move—to attack infection or heal a wound, for example—cellular proteins send and receive a cascade of signals that directs the cells to the right place at the right time. It’s a process cancer cells can hijack to spread to new tissues and organs. Now, a team...
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Solving long-sought protein structure opens new avenues for treating disease
by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys have identified the long-sought structure of an essential blood protein: vitronectin. Knowing the protein’s structure—an advance that enables rational drug design—could lead to medicines that kill multi-drug-resistant bacteria, halt cancer metastasis, treat age-related macular degeneration (AMD) and more. The study was published in...
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Blocking inflammatory pathway key to preventing brain metastasis from melanoma
by Tel Aviv University Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising. A new Tel Aviv University study finds that melanoma brain metastasis occurs when tumor cells “hijack” an inflammatory pathway in the brain. Blocking this pathway...
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Predicting breast cancer metastasis by cell behavior instead of genetics
by Gina Wadas, Johns Hopkins University Researchers and clinicians don’t fully understand why some cancers spread and others do not. What they do know is that when cancer does spread, it dramatically decreases survival rates. If physicians could predict the likelihood that primary tumors will metastasize, they would be able to choose the best treatment options for patients....
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From microfluidics to metastasis
Circulating tumor cells (CTCs) — an intermediate form of cancer cell between a primary and metastatic tumor cell — carry a treasure trove of information that is critical to treating cancer. Numerous engineering advancements over the years have made it possible to extract cells via liquid biopsy and analyze them to monitor an individual patient’s...