JUNE 11, 2024 by Flinders University Credit: Cancers (2024). DOI: 10.3390/cancers16112055 Flinders University researchers have analyzed how an antidiabetic treatment could help control the growth of tumors, potentially paving the way for the design of better cancer treatments. The new study investigated what happens when metformin, a type 2 diabetes medication, is used to treat...
Written by Jennifer Gershman, PharmD, CPh, PACS | Reviewed by Austin Ulrich, PharmD, BCACP Key takeaways: Metformin is a first-choice medication for managing Type 2 diabetes. But it can sometimes lower your vitamin B12 levels.Many foods, dietary supplements, and prescription medications contain vitamin B12 (cobalamin) to some degree. If your vitamin B12 levels get too...
Written by Timothy Aungst, PharmD | Reviewed by Amy B. Gragnolati, PharmD, BCPS AsiaVision/E+ via Getty Images Key takeaways: Metformin is a common first-choice treatment for Type 2 diabetes. It helps lower your blood sugar levels and can lower your risk of cardiovascular events like heart attacks. It also has a low risk of causing...
Megan Brooks October 31, 2023 TOPLINE: New research suggests terminating metformin may raise the risk for dementia in older adults with type 2 diabetes, providing more evidence of metformin’s potential neuroprotective effects. METHODOLOGY: TAKEAWAY: IN PRACTICE: The findings “corroborate the largely consistent evidence from other observational studies showing an association between metformin use and lower dementia incidence...
by Tim Tedeschi, University of Cincinnati Credit: Unsplash/CC0 Public Domain A new large-scale study led by researchers at the University of Cincinnati and Northwell Health, New York’s largest health care provider, found the drug metformin can help prevent or reduce weight gain in youth taking medication to treat bipolar disorder. The collaborative team presented its findings...
Joshua J. Neumiller, PharmD, CDCES; Radica Z. Alicic, MD, MSc DISCLOSURES August 15, 2023Initially approved by the US Food and Drug Administration (FDA) in 1994, metformin has been the preferred first-line glucose-lowering agent for patients with type 2 diabetes (T2D) owing to its effectiveness, low hypoglycemia risk, weight neutrality, long clinical track record of safety,...
Joshua J. Neumiller, PharmD, CDCES; Radica Z. Alicic, MD, MSc Initially approved by the US Food and Drug Administration (FDA) in 1994, metformin has been the preferred first-line glucose-lowering agent for patients with type 2 diabetes (T2D) owing to its effectiveness, low hypoglycemia risk, weight neutrality, long clinical track record of safety, and affordability. However,...
by Impact Journals LLC Variable changes in phosphorylation of S6 kinase 1 was observed in both cohorts. Credit: Oncotarget (2023). DOI: 10.18632/oncotarget.28458 A new research paper titled “Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer” has been published in Oncotarget ....
by Impact Journals LLC Summary schematic of MET+LEU effects during SD in muscle cells. Credit: 2023 Petrocelli et al. Aging coincides with the accumulation of senescent cells within skeletal muscle that produce inflammatory products, known as the senescence-associated secretory phenotype, but the relationship of senescent cells to muscle atrophy is unclear. Previously, researchers found that...
BY JOSEPH GUSTAITIS | DECEMBER 30, 2022 Metformin, the most popular blood sugar-lowering medicine in the world, seems to be turning out to be the Swiss Army knife of medications. In recent years, there have been reports that metformin appears to improve mitochondrial function in people with diabetes, that it can help in chronic kidney disease (CKD), and...
