For over 60 years, scientists have been baffled by how metformin, the trusted diabetes drug, works at the cellular level. A new study from Northwestern Medicine uncovers a surprising mechanism tied to the cell’s mitochondria, shedding light on its role in lowering blood sugar and even slowing cancer growth. Arezki Amiri Published on December 20,...
Tag: <span>Metformin</span>
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Better Than Metformin: New Diabetes Wonder-Drug Slashes Fat and Blood Sugar
By Kumamoto UniversityDecember 14, 202484 Comments3 Mins Read FacebookTwitterPinterestTelegram Share HPH-15 offers multiple benefits for managing Type 2 diabetes, including effective blood glucose control, reduced risk of lactic acidosis, improved insulin resistance, and suppression of fat buildup and fibrosis in the liver and fat tissue, with these effects observed in studies using muscle, liver, and fat...
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Diabetes drug metformin might help fight lung cancer
by Ernie Mundell Already the go-to drug of choice for millions with type 2 diabetes, metformin might also fight lung cancer if those patients have it as well, new research shows. Metformin appears to help boost the benefits of immunotherapy drugs used to fight lung tumors, according to a team led by Dr. Sai Yendamuri. He...
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Diabetes meds metformin and GLP-1s can also curb asthma, research finds
by Ernie Mundell Drugs already taken by millions of diabetes patients appear to also help slash asthma attacks by up to 70%, new British research shows. The two drugs are metformin, one of the most widely used diabetes medications, and the GLP-1 class of medications that includes Ozempic, Mounjaro, and Saxenda. A study of nearly 13,000...
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Metformin: An Unexpected Ally Against Long COVID?
Metformin use in adults with type 2 diabetes (T2D) is associated with a slightly lower incidence of long COVID and death within 180 days after SARS-CoV-2 infection. METHODOLOGY: TAKEAWAY: IN PRACTICE: “The incidence of PASC was lower when defined by [International Classification of Diseases] code compared with a computable phenotype in both databases,” the authors...
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Insulin and metformin combo aids diabetic foot ulcer healing, new study finds
September 4, 2024 by Michigan State University Credit: ACS Pharmacology & Translational Science (2024). DOI: 10.1021/acsptsci.4c00418People with chronic diabetic foot ulcers could soon have a new way to treat their wounds for faster healing and fewer hospital stays. Researchers from Michigan State University and South Shore Hospital have uncovered that the combination of two common...
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Study reveals metformin’s role in slowing colorectal cancer cell growth
JUNE 11, 2024 by Flinders University Credit: Cancers (2024). DOI: 10.3390/cancers16112055 Flinders University researchers have analyzed how an antidiabetic treatment could help control the growth of tumors, potentially paving the way for the design of better cancer treatments. The new study investigated what happens when metformin, a type 2 diabetes medication, is used to treat...
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What to Know About Taking Vitamin B12 and Metformin
Written by Jennifer Gershman, PharmD, CPh, PACS | Reviewed by Austin Ulrich, PharmD, BCACP Key takeaways: Metformin is a first-choice medication for managing Type 2 diabetes. But it can sometimes lower your vitamin B12 levels.Many foods, dietary supplements, and prescription medications contain vitamin B12 (cobalamin) to some degree. If your vitamin B12 levels get too...
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Long-Term Side Effects of Metformin: What Are the Risks?
Written by Timothy Aungst, PharmD | Reviewed by Amy B. Gragnolati, PharmD, BCPS AsiaVision/E+ via Getty Images Key takeaways: Metformin is a common first-choice treatment for Type 2 diabetes. It helps lower your blood sugar levels and can lower your risk of cardiovascular events like heart attacks. It also has a low risk of causing...
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More Evidence Metformin May Be Neuroprotective
Megan Brooks October 31, 2023 TOPLINE: New research suggests terminating metformin may raise the risk for dementia in older adults with type 2 diabetes, providing more evidence of metformin’s potential neuroprotective effects. METHODOLOGY: TAKEAWAY: IN PRACTICE: The findings “corroborate the largely consistent evidence from other observational studies showing an association between metformin use and lower dementia incidence...