WASHINGTON STATE UNIVERSITY SPOKANE, Wash. – Diabetic patients taking the natural product goldenseal while taking the prescription drug metformin may be unwittingly sabotaging their efforts to maintain healthy blood glucose levels. This concern arose from a recent study published in the journal Clinical Pharmacology & Therapeutics. Metformin–the world’s most-prescribed oral glucose-lowering medication–was included in a cocktail of selected drugs...
Tag: <span>Metformin</span>
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Recall report: Nostrum recalls another lot of metformin as carcinogen concerns continue
Conner Mitchell Associate Editor For the second time in January and the third time in the last two months, a Kansas City, MO laboratory has pulled a lot of generic metformin from the shelves after it was found to contain higher-than-allowed levels of a probable human carcinogen. The FDA on Tuesday announced that Nostrum Laboratories was voluntarily...
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Metformin use reduces risk of death for patients with COVID-19 and diabetes
UNIVERSITY OF ALABAMA AT BIRMINGHAM IMAGE: ANATH SHALEV CREDIT: UAB BIRMINGHAM, Ala. – Use of the diabetes drug metformin — before a diagnosis of COVID-19 — is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes...
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Nostrum expands recall of diabetes drug metformin after carcinogen concerns
Conner Mitchell Associate Editor Generic metformin has been a thorn in drugmakers’ sides for months after a probable human carcinogen was found in tested lots. Now, one of the companies is expanding its recall to another lot of the drug. Nostrum Laboratories out of Kansas City, MO voluntarily recalled one lot of metformin HCl extended release...
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Metformin treatment linked to slowed cognitive decline
GARVAN INSTITUTE OF MEDICAL RESEARCH Metformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwide, with millions of individuals using it to optimise their blood glucose levels. A new research study, conducted over six years in the Sydney Memory and Ageing Study in 1037 Australians (aged 70...
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A diabetes drug can combat some of the more severe COVID-19 symptoms in women
A diabetes drug called Metformin was found to reduce the fatality rate of women with the coronavirus by as much as 24%. The drug did not appear to have an impact on men with the coronavirus. The coronavirus pandemic may persist for as long as two years without an effective vaccine. Dr. Anthony Fauci recently...
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GDF15 mediates the effects of metformin on body weight and energy balance
Anthony P. Coll, Michael Chen, Stephen O’Rahilly Nature (2019) , Cite this article, 53 Altmetric, Metrics details AbstractMetformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk1,2. Over 60% of this effect is attributable to the ability of metformin to lower body weight in a...
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Metformin may lower dementia risk in black patients with T2DM
Jeffrey F. Scherrer, Ph.D., from Saint Louis University School of Medicine, and colleagues used Veterans Health Administration medical record data (2000 to 2015) to identify 73,761 African-American and white patients (aged ≥50 years) who were free of dementia and diabetes medications at baseline (2000 and 2001) but subsequently initiated metformin or sulfonylurea monotherapy. When controlling for other variables, the researchers found...
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Is a diabetes drug the key to aggressive breast cancer?
By Ana Sandoiu Fact checked by Paula Field New research finds that the diabetes drug metformin changes stem cancer cells in a way that makes them easier to target with a new form of treatment. The findings could help treat triple-negative breast cancer, which is particularly aggressive. Triple-negative breast cancer is an aggressive form of breast cancer...
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Metformin may cut mortality risk in post-pancreatitis diabetes
Jaelim Cho, M.D., M.P.H., from the University of Auckland in New Zealand, and colleagues used nationwide pharmaceutical dispensing data (from 2006 to 2015) linked to hospital discharge data to identify 1,862 individuals with PCRD or PPDM. The researchers found that in individuals with PCRD, ever users of metformin (adjusted hazard ratio [aHR], 0.54) and ever users of insulin (aHR,...