by University of North Carolina Health Care Hepatitus A virus particles (pink) trapped in lysosomes (yellow intracellular organelles), unable to initiate replication in the cytoplasm of cells due to UCGC enzyme being knocked out. Credit: Maryna Kapustina, PhD, UNC School of Medicine How hepatitis A virus (HAV) manages to enter liver cells called hepatocytes and...
Tag: <span>Microbiology</span>
New gut-brain link: how gut mucus could help treat brain disorders
by RMIT University Mucus is the first line of defence against bad bacteria in our gut. But could it also be part of our defence against diseases of the brain? Bacterial imbalance in the gut is linked with Alzheimer’s disease, autism and other brain disorders, yet the exact causes are unclear. Now a new research...
Ketogenic diets alter gut microbiome in humans, mice
by University of California, San Francisco Low-carb, high-fat ketogenic diets, which have attracted public interest in recent years for their proposed benefits in lowering inflammation and promoting weight loss and heart health, have a dramatic impact on the microbes residing in the human gut, collectively referred to as the microbiome, according to a new UC...
Cracking the Lyme disease code
NEWS RELEASE 30-APR-2020 Cracking the Lyme disease code WASHINGTON STATE UNIVERSITY PRINT E-MAIL IMAGE: THIS IS ABDUL LONE. view more CREDIT: WSU The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn’t linger for a lifetime. Troy Bankhead, associate professor in WSU’s...
Revealed: The deadly superbugs lurking in more than nine in ten make-up bags
by Aston University The vast majority of in-use make-up products such as beauty blenders, mascara and lip gloss are contaminated with potentially life threatening superbugs, new research from Aston University published in the Journal of Applied Microbiology has revealed. Make-up products used every day by millions of people in the UK are contaminated with potentially...
When your microbiome and your genome aren’t a good combination
Researchers led by a team from Osaka University find a link between the gut microbiome, the host genome, and rheumatoid arthritis in Japanese patients OSAKA UNIVERSITY Osaka, Japan – One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being. In addition to extracting...
Pathogen engineered to self-destruct underlies cancer vaccine platform
by American Society for Microbiology A team of investigators has developed a cancer vaccine technology using live, attenuated pathogens as vectors. A feature of the vaccine causes these bacteria to self-destruct once they’ve done their job, making it safe for use in humans. The research is published in Infection and Immunity, a journal of the American Society for Microbiology. Unlike “prophylactic” vaccines that protect...
Advance in CAR T-cell therapy eliminates severe side effects
by University of Southern California An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows. “This is a major improvement,” said Si-Yi Chen of the USC Norris Comprehensive Cancer Center, professor in...
Biochemical switches identified that could be triggered to treat muscle, brain disorders
ST. JUDE CHILDREN’S RESEARCH HOSPITAL St. Jude Children’s Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells. Such buildup is central to the pathology of three related diseases: inclusion body myopathy...