People sometimes suffer toxic side effects from drugs that help many others. Yale scientists have identified a surprising explanation—the gut microbiome. Credit: CC0 Public Domain The research, published Feb. 8 in the journal Science, describes how bacteria in the gut can transform three drugs into harmful compounds. “If we can understand the microbiome’s contributions to...
Tag: <span>Microbiome</span>
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Medication for severe acne alters skin microbiome
Isotretinoin, a form of vitamin A, has been prescribed to treat acne for decades. It reduces oil production in the skin, which helps prevent acne from forming. But new research from Washington University School of Medicine in St. Louis has uncovered a previously unknown benefit of the medication. It shifts the skin microbiome of acne...
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Regeneration in the digestive tract
The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them. Whether and how the intestinal flora will subsequently recover has been investigated by a research team that included scientists from the MDC. The results have been published in the scientific journal Nature Microbiology. IMAGE: THIS IS A...
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Mannose’s unexpected effects on the microbiome and weight gain
Scientists continue to unravel links between body weight and the gut microbiome. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) report an unexpected finding: mice fed a fatty diet and mannose, a sugar, were protected from weight gain, leaner, and more fit—and this effect tracked with changes in the gut microbiome. The study...
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Depleting microbiome with antibiotics can affect glucose metabolism
A new study from the Salk Institute has found that mice that have their microbiomes depleted with antibiotics have decreased levels of glucose in their blood and better insulin sensitivity. The research has implications for understanding the role of the microbiome in diabetes. It also could lead to better insight into the side effects seen in people...
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Depleting microbiome with antibiotics can affect glucose metabolism
Salk Institute study in mice finds microbiome-induced changes in the liver may influence diabetes SALK INSTITUTE LA JOLLA–(July 23, 2018) A new study from the Salk Institute has found that mice that have their microbiomes depleted with antibiotics have decreased levels of glucose in their blood and better insulin sensitivity. The research has implications for...
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Gut microbiome showed positive response to vegetarian diet in two weeks
The research team from ITMO University and collaborators analyzed the impact of short-term changes in diet on the condition of the gut microbiome. Assessing changes in the microbiome structure of 248 volunteers, the researchers concluded that a diet enriched with food fiber significantly changes the balance of gut bacterial species in two weeks. Obtained results...
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We are never alone – microbiome is our friend
There is a joke that you’re never lonely just think of the many organisms with whom you share your own body. While the human organism itself is said to contain about 37 trillion human cells, the microbiome – and the bulk of bacteria making it up – means an additional 30-50 trillion cells. That means that every...
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Study reveals connection between microbiome and autoimmune disorders
Many people associate the word “bacteria” with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. “The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens...